产房内胎盘输血联合呼吸支持的研究进展

Research progress on placental transfusion combined with respiratory support in delivery room

新生儿特别是极早产儿或发生窒息的新生儿生后需要胎盘输血维持血压稳定和呼吸支持维持肺部扩张。临床实践中常先行延迟脐带结扎,断脐后再给予呼吸支持。但延长呼吸支持开始时间存在一定的风险,因此现已有临床相关研究开展胎盘输血同时呼吸支持。本文就胎盘输血联合呼吸支持的生理基础、不同实施形式和对新生儿的影响进行综述。

Neonates,especially extremely preterm infants or those who have suffered birth asphyxia,require placental transfusion to stabilize blood pressure and respiratory support to maintain pulmonary expansion after birth.In clinical practices,it is common to first perform delayed cord clamping,followed by respiratory support after the umbilical cord has been cut.Nevertheless,as the prolonged onset of respiratory support carries risks,recent clinical studies have been investigating the possibility of implementing concurrent placental transfusion and respiratory support.This review discusses the physiological principles of placental transfusion combined with respiratory support,different methods of implementation,and their effects on neonates.