2株牦牛源枯草芽孢杆菌的药敏及抑菌试验

Drug Susceptible and Bacteriostatic Tests of Two Strains of Bacillus Subtilis of Yak Origin

该文对2株牦牛源枯草芽孢杆菌进行10种抗菌药物的药敏试验和3种致病菌的抑菌试验。结果表明,在药敏试验中BS-1菌株对头孢曲松、链霉素、复方新诺明中度敏感,BS-2菌株对头孢曲松中度敏感,2株菌均对卡那霉素、氯霉素、诺氟沙星、阿米卡星、环丙沙星、庆大霉素、氧氟沙星高度敏感;在抑菌试验中BS-1、BS-2对大肠杆菌、沙门氏菌、金黄色葡萄球菌3种致病菌均有一定的抑菌活性,但BS-2抑菌活性相对较强,具有开发为益生菌制剂的潜能。

Two yak-derived Bacillus subtilis strains were subjected to a drug susceptible y test for 10 antimicrobial drugs and an inhibition test for three pathogenic bacteria.The results showed that BS-1 strain was moderately sensitive to ceftriaxone,streptomycin and cotrimoxazole in the drug susceptible test,and BS-2 strain was moderately sensitive to ceftriaxone,and both strains were highly sensitive to kanamycin,chloramphenicol,norfloxacin,amikacin,ciprofloxacin,gentamicin,and ofloxacin;and in bacteriostatic test BS-1 and BS-2 had certain bacteriostatic activity on Escherichia coli,Salmonella,and Staphylococcus aureus.But the bacteriostatic activity of BS-2 is relatively stronger,and it has the potential of being developed into a probiotic preparation.