偏头痛患者残疾程度影响因素分析

Influencing factors of the degree of disability in migraine patients

目的探讨引起偏头痛患者中重度残疾的影响因素。方法选择2022年9月—2024年1月就诊于包头市中心医院和包头市第八医院神经内科门诊或住院部确诊的偏头痛患者。根据偏头痛残疾程度评估问卷得分将纳入患者分为无或轻度残疾组和中重度残疾组。收集比较两组患者的社会人口学、疾病特征以及量表信息,采用多因素logistic回归模型探讨中重度残疾组偏头痛患者的影响因素。结果共纳入116例患者。其中,无或轻度残疾组49例,中重度残疾组67例。两组的性别、头痛病程、头痛严重程度、每个月头痛天数、药物过度使用、广泛性焦虑障碍量表、患者健康调查问卷量表、匹兹堡睡眠质量指数量表和头痛影响测试量表、蒙特利尔认知评估量表和36项简短健康状况调查问卷得分比较,差异均有统计学意义(P<0.05)。两组患者其他社会人口学信息、疾病特征比较,差异均无统计学意义(P>0.05)。多因素logistics回归分析结果显示,头痛天数、广泛性焦虑障碍量表得分、头痛影响测试量表得分和36项简短健康状况调查问卷得分是中重度残疾偏头痛患者的独立影响因素(P<0.05)。结论每个月头痛天数、焦虑及与健康相关的生活质量是偏头痛患者中重度残疾的影响因素。应重视早期对偏头痛患者进行影响因素的筛查和干预。

Objective To investigate the influencing factors of moderate to severe disability in migraine patients.Methods Patients diagnosed with migraine between September 2022 and January 2024 in the outpatient service or inpatient Department of Neurology of Baotou Central Hospital and Baotou Eighth Hospital were included.According to the scores of the Migraine Disability Assessment questionnaire,patients were divided into a group with no or mild disabilities and a group with moderate to severe disabilities.The sociodemographic,disease characteristics,and scale datas of two groups of patients were collected,and a multivariate logistic regression model was used to explore the influencing factors of moderate to severe disability in migraine patients.Results A total of 116 patients were included.Among them,there were 49 cases in the group with no or mild disabilities,and 67 cases in the group with moderate to severe disabilities.There were statistically significant differences in gender,duration of headache,severity of headache,number of headache days per month,drug overuse,the scores of Generalized Anxiety Disorder-7 scale,the scores of Patient Health Questionnaire-9 scale,the scores of Pittsburgh Sleep Quality Index scale,the scores of Headache Impact Test scale,the scores of Montreal Cognitive Assessment scale,and the scores of 36-item Short-Form Health Survey questionnaires between the two groups (P<0.05). There was no statistically significant difference in other sociodemographic informationand disease characteristics between the two groups of patients (P>0.05). The results of multivariate logistic regressionanalysis showed that the number of headache days per month, the scores of Generalized Anxiety Disorder-7 scale, thescores of Headache Impact Test scale, and the scores of 36-item Short-Form Health Survey questionnaire wereindependent influencing factors for moderate to severe disability in migraine patients (P<0.05). Conclusions Headacheduration, anxiety disorders and health-related quality of life are influencing factors for moderate to severe disability inmigraine patients. Early screening and intervention of influencing factors for migraine patients should be emphasized.