椎针通督循经疗法联合通经解痉汤治疗脑梗死后肢体痉挛临床研究

Clinical Study on Zhuizhen Tongdu Xunjing Therapy/Decoction Combined with Tongjing Jiejing Decoction for Limb Spasticity After Cerebral Infarction

目的:观察椎针通督循经疗法联合通经解痉汤治疗脑梗死后肢体痉挛的临床疗效。方法:选取86例脑梗死后肢体痉挛患者,按随机数字表法分为对照组和观察组各43例。2组均接受抗痉挛药物、康复训练等常规治疗,对照组在常规治疗基础上加用通经解痉汤,观察组在对照组基础上加用椎针通督循经疗法。2组均连续治疗2个月。比较2组治疗前后肢体痉挛[改良Ashworth痉挛评价量表(MAS)]、神经功能指标[神经元特异性烯醇化酶(NSE)、中枢神经特异性蛋白(S100β)]、日常生活能力[改良巴氏指数评定表(MBI)]改善情况。结果:治疗后,2组MAS评分较治疗前下降(P<0.05),且观察组MAS评分低于对照组(P<0.05)。治疗后,2组NSE、S100β水平较治疗前下降(P<0.05),且观察组NSE、S100β水平低于对照组(P<0.05)。治疗后,2组MBI评分较治疗前上升(P<0.05),且观察组MBI评分高于对照组(P<0.05)。结论:椎针通督循经疗法联合通经解痉汤能改善脑梗死后肢体痉挛患者神经功能,减轻痉挛发作,提高日常生活能力。

Objective:To observe the clinical effect of Zhuizhen Tongdu Xunjing Therapy Decoction combined with Tongjing Jiejing Decoction on limb spasticity after cerebral infarction.Methods:A total of 86 patients with limb spasticity after cerebral infarction were selected and divided into the control group and the observation group according to the random number table method,with 43 cases in each group.Both groups received conventional treatments such as anti-spastic medicine and rehabilitation training.The control group was added with Tongjing Jiejing Decoction based on conventional treatment,and the observation group was added with Zhuizhen Tongdu Xunjing Therapy based on the treatment of the control group.Both groups were treated for 2 months.The improvement of limb spasticity[Modified Ashworth Scale(MAS)],neurological function indexes[neuron-specific enolase(NSE),central nervous system specific protein(S100p)]and ability of daily living[modified Barthel Index(MBI)]were compared before and after treatment between the two groups.Results:After treatment,the MAS scores in the two groups were decreased when compared with those before treatment(P<0.05),and the MAs score in the observation group was lower than that in the control group(P<0.05).After treatment,the levels of NSE and S100βin the two groups were decreased when compared with those before treatment(P<0.05),and the levels of NSE and S100βin the observation group were lower than those in the control group(P<0.05).After treatment,the MBl scores in the two groups were increased when compared with those before treatment(P<0.05),and the MBl score in the observation group was higher than that in the control group(P<0.05).Conclusion:Zhuizhen Tongdu Xunjing Therapy Decoction combined with Tongjing Jiejing Decoction can improve the neurological function of patients with limb spasticity after cerebral infarction,reduce spasms,and improve the ability of daily living.