针刺治疗多囊卵巢综合征机制研究进展

Research Progress on Mechanism of Acupuncture Treatment for PCOS

多囊卵巢综合征(PCOS)是妇科常见的生殖内分泌疾病,发病率约为6%~10%,生殖期女性患病率明显升高。近年来,针刺广泛应用于治疗PCOS,且疗效显著,相关机制研究亦逐步展开。本研究介绍针灸改善PCOS的主要作用机制及当前研究进展,如针灸治疗可调节HPOA轴,降低雄激素,减轻炎症反应,调节肠道菌群,调节情志,改善胰岛素抵抗、卵巢功能、子宫内膜容受性、氧化应激和血管异常等。

Polycystic ovary syndrome(PCOS)is a common reproductive endocrine disorder in gynecology,with an incidence of approximately about 6%to 10%,and the prevalence among women of reproductive age is significantly higher.In recent years,acupuncture has been increasingly widely applied in the clinical treatment of PCOS,with a significant efficacy,and related mechanistic research is gradually unfolding.This study introduced the main mechanisms of acupuncture in improving PCOS and current research progress,such as regulating the HPOA axis,reducing androgens,alleviating inflammatory response,regulating intestinal flora,regulating emotions,improving insulin resistance,ovarian function,endometrial receptivity,oxidative stress and vascular abnormalities,among others.It aimed to provide a theoretical basis and reference for the basic research and clinical treatment of this disease.