基于Web of science和CNKI对全球MSTN基因的研究进展分析

Research and Analysis of Global MSTN Gene Based on Web of Science and CNKI

肌肉生长抑制素(Myostatin,MSTN)作为动物肌肉生长的负调节因子,对提高动物的肌肉量和瘦肉率具有重要意义。该文采用文献计量学方法,以"MSTN/GDF-8/Myostatin"为检索词对2000—2020年期间Web of Science核心合集数据库和CNKI中国学术期刊全文数据库收录的相关论文进行主题检索,并使用Excel 2016、GraphPad Prism 8.4.0和VOS viewer软件对数据进行可视化处理。结果显示,通过Web of Science平台共检索到相关MSTN的SCI论文4404篇,其中中国发表的论文675篇。CNKI中国学术期刊全文数据库内检索出759篇论文。全球关于MSTN的发文量在2000—2020年呈现总体上升的趋势,美国和一些畜牧业发达的国家对MSTN的研究较为深入;中国学者的发文量虽多但其篇均被引频次较低,需从不同维度开展该领域研究并加强机构间合作,提高文章水平,进而缩小差距。目前关于MSTN的研究集中于分子生物学、农学、遗传学、生物技术与微生物学四大领域。对于农学领域提高肉类品质和产量依旧十分重要,因此需要提高对MSTN如何影响肌肉发育及脂肪蓄积方面的认识。本文通过统计分析及可视化处理,为我国科研人员了解MSTN相关的研究动态和研究方向、并以此开展优良品种培育提供信息帮助。

Myostatin(MSTN),as a negative regulator of animal muscle growth,plays an important role in improving animal muscle production and lean meat rate.In this study,a bibliometric search was conducted using "MSTN/GDF-8/Myostatin" as the search term for the relevant papers included in the Web of Science Core Collection database and CNKI China Academic Journal Full Text Database from 2000 to 2020.The data were visualized using Excel 2016,GraphPad Prism 8.4.0 and VOS viewer software.The results showed that a total of 4404 SCI papers on MSTN were retrieved through the Web of Science platform,among which 675 papers were published in China.The 759 papers were retrieved within the CNKI Chinese Academic Journals Full Text Database.According to statistics,the number of published papers on MSTN in the world showed an overall upward trend from 2000to 2020.The United States and some countries with developed animal husbandry have conducted more in-depth research on MSTN;although Chinese scholars has published a large number of papers,its average citation frequency is relatively low.There is a need for scholars to conduct research in this area from different dimensions and to strengthen inter-institutional cooperation in order to narrow the gap and improve papers.In addition,the research directions of MSTN are concentrated in the four fields of molecular biology,agronomy,genetics,biotechnology and microbiology.This paper provides statistical analysis and visualization to help researchers in China to understand the research trends and directions related to MSTN and to develop excellent breeding varieties.