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日本食道学会-AB分型在预测食管浅表鳞状细胞癌浸润深度中的应用

The application of the Japanese Esophageal Society AB typing in predicting the invasion depth of superficial squamous cell carcinoma of the esophagus
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摘要 目的 探讨基于鳞状上皮乳头内毛细血管袢(IPCLs)的日本食道学会(JES)-AB分型在预测食管浅表鳞状细胞癌(SESCC)浸润深度中的应用。方法 收集2018年1月至2022年12月期间接受内镜下黏膜剥离术(ESD)治疗的130例SESCC患者资料,所有病变均按JES-AB分型对IPCLs进行分型,并与ESD病理进行比对,评估JES-AB分型对SESCC浸润深度判断的准确性。结果 130例中共有159处病变。IPCLs B1型107处,病理提示T1a-EP/LPM 102处,T1a-MM/T1b-SM1 4处,T1b-SM2或更深浸润1处,B1血管诊断T1a-EP/Tla-LPM的敏感性、特异性、阳性预测值(PPV)、阴性预测值(NPV)、诊断准确度分别为80.95%、84.85%、95.3 3%、53.85%、81.76%;IPCLs B2型47处,病理提示T1a-EP/LPM 24处,T1a-MM/T1b-SM1 20处,T1b-SM2或更深浸润3处,B2血管诊断T1aMM/T1b-SM1的敏感性、特异性、PPV、NPV、诊断准确度分别为80.00%、79.85%、42.55%、95.54%、79.87;B%IPCLs3型5处,病理提示T1a-MM/T1b-SM1 1处,T1b-SM2或更深浸润4处,B3血管诊断T1b-SM2及以深的敏感性、特异性、PPV、NPV、诊断准确度分别为50.00%、99.34%、80.00%、97.40%、96.86%。无血管区(AVA)分型AVA-small、AVAmiddle、AVA-large预测浸润深度的敏感性、特异性分别为22.22%、96.97%,52.00%、94.03%,25.00%、99.34%。结论JES-AB分型可用于SESCC浸润深度的预测,具有较高的的诊断准确性。
作者 陆宏娜 郭雯莹 汪春年 邓茜 翁烃 张良舜 许丰 LU Hongna;GUO Wenying;WANG Chunnian
出处 《现代实用医学》 2024年第5期606-608,F0003,共4页 Modern Practical Medicine
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