精神分裂症患者合并代谢综合征的研究进展

Research progress on metabolic syndrome in patients with schizophrenia

精神分裂症是一种严重的精神疾病,在全球死亡率显著升高的众多精神疾病中精神分裂症占首位,有大量研究表明精神分裂症患者存在一定的代谢异常,证实代谢综合征在精神分裂症患者中比在普通人群中更常见,且研究表明精神分裂症患者的平均死亡时间比普通人群早25年,这种风险大部分是由于慢性疾病造成的,患者的冠心病的发病率和患病率特别高,严重时致患者失去生命。另外有研究表明精神分裂症患者可能更容易患代谢综合征,而这与是否服用精神病药并无关系,也有研究说明相当一部分精神分裂症患者先出现代谢综合征,当然这需要更多的研究进一步证实。目前该疾病的代谢领域是众多研究学者关注的重点领域,且代谢综合征与精神分裂症两者出现的早晚以及是否有相关性需进一步研究,本文将综述精神分裂症患者合并代谢综合征的研究进展。

Schizophrenia is a serious mental illness that accounts for the largest number of mental illnesses with significantly increased mortality worldwide.Numerous studies have shown that people with schizophrenia have certain metabolic abnormalities,confirming that metabolic syndrome is more common in people with schizophrenia than in the general population,and studies have shown that people with schizophrenia die on average 25 years earlier than the general population.Much of this risk is due to chronic diseases,with a particularly high incidence and prevalence of coronary heart disease,which can lead to the loss of life in severe cases.There are also studies that suggest that people with schizophrenia may be more susceptible to metabolic syndrome,regardless of whether they take psychiatric drugs.There are also studies that show that a significant proportion of patients with schizophrenia develop metabolic syndrome first,although more research is needed to confirm this.At present,the metabolic field of this disease is the focus of many researchers,and the early and late appearance of metabolic syndrome and schizophrenia and whether there is a correlation need further research.