基于中断时间序列分析司美格鲁肽控费管理的实施效果

Implementation effect of cost control management of semaglutide injection based on interrupted time series analysis

目的评价司美格鲁肽注射液控费管理的实施效果。方法收集首都医科大学附属北京安贞医院使用司美格鲁肽注射液的门诊处方信息,利用中断时间序列分析法评价专项处方管理干预前和干预后例均费用的变化。结果通过专项处方管理的实施,可有效降低患者例均费用[干预前(740.47±410.82)元,干预后(644.04±159.23)元]。以例均费用作为因变量,模拟中断线性回归模型为Y=732.99-0.83T1-68.33T2+1.77T3+ε。干预前例均费用以每周0.83元的趋势缓慢下降(P>0.05),干预的瞬时效果为例均费用降低了68.33元(P<0.05),在使用人数逐渐增多的情况下,干预后例均费用以每周0.94元的趋势上升(P>0.05)。结论专项处方管理能有效降低司美格鲁肽注射液的例均费用,合理控制药品费用。

Objective To evaluate the implementation effect of cost management of semaglutide injection.Methods The outpatient prescription information for semaglutide injection in Beijing Anzhen Hospital,Capital Medical University was collected from February 24 to September 27,2022.Interrupted time series analysis was used to evaluate the changes in cost per patient before and after the intervention of prescription management.Results By the implementation of special prescription management,the cost per patient was effectively reduced[pre-intervention(724.76±32.20)yuan vs.post-intervention(660.86±8.35)yuan].Using cost per patient as the dependent variable,the regression model of the interrupted time series equation was Y=732.99-0.83T1-68.33T2+1.77T3+ε.The cost per patient showed a slow downward trend of 0.83 yuan per week before the intervention(P>0.05),and the immediate effect of the intervention was a decrease of 68.33 yuan in cost per patient(P<0.05).After the intervention,the cost per patient showed a trend of increasing by 0.94 yuan per week(P>0.05)as the number of users gradually increased.Conclusion Prescription management can effectively reduce the cost per patient of semaglutide injection and control medication expenses reasonably.