红枣多糖的生物活性及作用机制研究进展

Research Progress on the Bioactivity and Mechanisms of Jujube Polysaccharides

红枣在中国作为食物和药材的历史已有数千年,其营养价值一直受到人们的认可,包含了多种对人体有益的健康活性成分。其中红枣多糖是红枣中的最主要生物活性成分之一,大量研究表明红枣多糖可以通过不同作用机制或多种作用机制协同来实现抗氧化、抗炎、抗肿瘤、免疫调节、抗疲劳、保肝、降血糖、降血脂等多种生物活性。本文概述了红枣多糖的理化性质和构效关系,并总结了近年来国内外有关红枣多糖生物活性及作用机制的研究进展,并以此为基础对红枣多糖应用于多种疾病的治疗前景进行了展望,以期为红枣多糖的进一步研究和生产其相关的治疗药物提供参考。

Jujube has a history of being used as both food and herbal medicine in China for thousands of years.Its nutritional value has long been recognized,as it contains various health-promoting bioactive components.Jujube polysaccharides are one of the major bioactive constituents.Extensive studies have shown that jujube polysaccharides exert multiple biological activities,such as antioxidant,anti-inflammatory,anti-tumor,immune regulatory,anti-fatigue,liverprotective,blood sugar-lowering,and blood lipid-lowering effects,through different or synergistic mechanisms.This article provides an overview of the physicochemical properties and structure-activity relationship of jujube polysaccharides,and summarizes the research progress on the bioactivity and mechanisms of jujube polysaccharides,both domestically and internationally in recent years.Based on these findings,the therapeutic potential of jujube polysaccharides for various diseases is discussed,aiming to provide references for further research and the development of related medicinal treatments involving jujube polysaccharides.