登革热脑炎伴降钙素原升高1例报道

Dengue fever encephalitis with elevated procalcitonin levels:A case report

该文报道了1例患登革热脑炎的年轻女性患者。收集了患者的临床症状和体征、生化标志物、影像学表现、宏基因检测等资料,并查阅相关文献。该患者以“发热、头痛4 d,腹泻、呕吐3 d,全身抽搐伴意识障碍3 h”为主诉被陆军军医大学第一附属医院收入院。入院第2天脑脊液宏基因组学检测(RNA)结果显示,登革热病毒1型,且伴有降钙素原升高,明确了登革热脑炎的诊断。临床上遇到发热、头痛、腹泻、呕吐,伴随降钙素原水平升高的患者,应怀疑登革热脑炎,并进行登革热血清学检查和脑脊液登革热RNA检测。

This article reports a young female patient with dengue fever encephalitis.Related clinical data were collected,including clinical symptoms and signs,biochemical markers,imaging findings,and metagenomics testing,and a literature review was performed.The patient was admitted to The First Affiliated Hospital of Army Medical University due to the chief complaint of“pyrexia and headache for 4 days and diarrhea and vomiting for 3 days”.On day 2 after admission,metagenomics testing of cerebrospinal fluid showed dengue virus type 1,with elevated procalcitonin levels,thereby confirming the diagnosis of dengue fever encephalitis.The possibility of dengue fever encephalitis should be considered for patients with pyrexia,headache,diarrhea,vomiting,and elevated procalcitonin levels,and serological tests for dengue fever and dengue fever RNA detection of cerebrospinal fluid should be performed.