低GI枸杞杂粮代餐粉的配方优化及其降血糖作用研究

Formula optimization of low GI barbary wolfberry multigrainmeal replacement powder and its hypoglycemic effect

为探究低血糖生成指数(glycemic index,GI)枸杞杂粮代餐粉的最佳配方及降血糖作用,该研究以黄豆、绿豆、黑豆、燕麦、苦荞和藜麦6种杂粮作为主要原料,再辅以药食同源的宁夏枸杞制备一种低GI枸杞杂粮代餐粉。以感官评分为指标,采用单因素试验、Plackett-Burman试验、最陡爬坡试验及Box-Behnken试验,优化低GI枸杞杂粮代餐粉配方,并通过建立Ⅱ型糖尿病小鼠模型,评价低GI枸杞杂粮代餐粉的降血糖效果。结果表明,枸杞杂粮代餐粉最佳配方为:黄豆粉添加量15.1%,绿豆粉添加量15.1%,黑豆粉添加量14%,燕麦粉添加量15.6%,苦荞粉添加量12.1%,藜麦粉添加量12.1%,枸杞粉添加量16%(均为质量分数)。低GI枸杞杂粮代餐粉可下调小鼠餐后血糖值并能够改善小鼠基本生长状况,但使小鼠的空腹血糖值缓慢上升且整体趋于平稳状态(P> 0.05)。

To explore the optimal formula and hypoglycemic effect of the low glycemic index(GI)barbary wolfberry of coarse grain meal replacement powder,in this study,six grains were used in soybean,mung bean,black bean,oats,Tartary buckwheat and quinoa as the main raw materials,and a low GI barbary wolfberry of coarse grain meal replacement powder was prepared from Ningxia barbary wolfberry with similar medicine and food.With the sensory score as an indicator,univariate test,Plackett-Burman test,steepest climbing test and Box-Behnken test were used to optimize the low GI barbary wolfberry coarse grain meal replacement powder formula,and the hypoglycemic effect of low GI barbary wolfberry coarse grain meal replacement powder was evaluated by establishing a type 2 diabetes mellitus mouse model.The results showed that the best formula of barbary wolfberry multigrain meal replacement powder was 15.1%of soybean flour,15.1%of mung bean flour,14%of black bean flour,15.6%of oat flour,12.1%of tartary buckwheat flour,12.1%of quinoa flour,and 16%of barbary wolfberry flour.Low GI barbary wolfberry multigrain meal replacement powder improved the postprandial blood glucose value and improved the basic growth status of mice,but the fasting blood glucose value slowly increased and became overall stable(P>0.05).