可穿戴设备在帕金森病患者围手术期运动功能检测中的应用

Application of wearable devices in perioperative motor function detection in patients with Parkinson's disease

目的探索可穿戴设备在帕金森患者围手术期中运动功能检测的作用。方法对2020年12月1日至2022年12月31日在十堰市太和医院接受脑深部电刺激(DBS)手术的17例患者进行回顾性研究,采用GraphPad Prism 9统计学软件对患者运动数据进行统计学分析,对患者手术前后运动检测的各数据进行t检验,手术前后运动检测的数据中各项指标与手术前后的帕金森病评定量表第Ⅲ部分(UPDRS-Ⅲ)评分采用Pearson相关系数进行线性回归分析。结果17例帕金森病(PD)患者UPDRS-Ⅲ评分由术前的(40.88±7.98)分降低为术后的(22.65±3.84)分(P<0.001),步长由术前的(32.25±6.25)cm增长为术后的(51.88±7.38)cm(P<0.001);5 m往返实验时间由术前的(17.14±3.61)s缩短为术后的(9.68±1.68)s(P<0.001);转圈实验时间由术前的(35.00±7.69)s缩短为术后的(16.60±2.48)s(P<0.001)。患者术前UPDRS-Ⅲ评分与步长呈负相关(r=-0.8843,P<0.001)、5 m往返实验时间呈正相关(r=0.8678,P<0.001)、转圈实验时间呈正相关(r=0.9080,P<0.001);术后UPDRS-Ⅲ评分与步长呈负相关(r=-0.9168,P<0.001)、5 m往返实验时间呈正相关(r=0.8695,P<0.001)、转圈实验时间呈正相关(r=0.8744,P<0.001)。结论可穿戴设备对PD患者进行运动功能检测的数据与患者UPDRS-Ⅲ评分具有较高一致性及强相关性,可以将可穿戴设备作为UPDRS-Ⅲ评分量表的补充项目,在PD患者围手术期对其进行更加精确、客观及定量的运动功能检测。

【Objective】To explore the role of wearable devices in the perioperative detection of motor function in Parkinson's disease(PD).【Methods】A retrospective study was conducted on 17 patients who underwent deep brain stimulation implantation in Taihe Hospital from December 1,2020 to December 31,2022,and the GraphPad Prism 9 statistical software was used to statistically analyze the patient's exercise data,and the data of the patient's preoperative and postoperative motion detection were t-tested.The indicators in the data of pre-and postoperative motion detection and the UPDRS-III score before and after surgery were analyzed by linear regression analysis using Pearson's correlation coefficient.【Results】The UPDRS-III score of patients decreased from preoperative 40.88±7.98 points to postoperative 22.65±3.84 points,the difference was statistically significant(P<0.001),and the step length increased from preoperative 32.25±6.25 cm to postoperative 51.88±7.38 cm,the difference between the two was statistically significant(P<0.001).The 5 m round-trip experimental time decreased from preoperative 17.14±3.61 s to postoperative 9.68±1.68 s,the difference was statistically significant(P<0.001),and the rotation experiment time was reduced from preoperative 35.00±7.69 s to postoperative 16.60±2.48 s,the difference was statistically significant(P<0.001).The preoperative UPDRS-Ⅲscore of 17 PD patients was consistent and correlated with step length(r=-0.8843,P<0.001),5 m round-trip experimental time(r=0.8678,P<0.001),and rotation experimental time(r=0.9080,P<0.001),and postoperative UPDRS-Ⅲscore was consistent and correlated with step length(r=-0.9168,P<0.001)and 5 m round-trip experimental time(r=0.8695,P<0.001)and the experimental time of rotation(r=0.8744,P<0.001).【Conclusion】The data of wearable devices for motor function detection in PD patients have a consistent and strong correlation with the UPDRS-III score,and wearable devices can be used as a supplementary item to the UPDRS-III,and the motor function detection of PD patients in the perioperative period is more accurate,objective and quantitative.