支气管扩张合并诺卡菌感染1例

A case report of bronchiectasis complicated by Nocardia infection

本文报道了山东大学附属威海市立医院1例支气管扩张合并诺卡菌感染的病例,同时进行了相关文献复习。该患者为一名68岁的女性,被诊断为支气管扩张,细菌培养中发现呼吸道样本中存在诺卡菌。经过详细的临床和实验室评估,最后确诊为诺卡菌感染。在治疗过程中,患者接受了第三代头孢菌素联合复方磺胺甲噁唑片治疗方案,取得了良好的疗效。本案例强调了认识支气管扩张合并诺卡菌感染的重要性,临床医生需加深对诺卡菌病临床特征、流行病学、治疗方案以及预后情况的理解,检验医生应提升病原学的检测水平,提高诺卡菌检测的灵敏度。

This article reported a patient with bronchiectasis who developed a Nocardia infection in Shandong University Affiliated Weihai Municipal Hospital,accompanied by a relevant literature review.The patient,a 68-year-old female diagnosed with bronchiectasis,had Nocardia identified in respiratory samples through bacterial culture.The diagnosis of Nocardia infection was confirmed by detailed clinical and laboratory assessments.During the treatment process,the patient received a regimen involving third-generation cephalosporins combined with sulfamethoxazole/trimethoprim,resulting in a positive therapeutic outcome.This case underscores the importance of recognizing Nocardia infections in patients with bronchiectasis.Clinicians need to deepen their understanding on the epidemiology,clinical characteristics,treatment approaches,and prognosis of Nocardia infections in bronchiectasis patients.Additionally,laboratory professionals should enhance the pathogen detection capabilities to increase the positivity rate of Nocardia testing.