成年人脑卒中后华勒变性的临床及影像学特点(附3例报告)

Clinical and imaging features of adult poststroke Wale's disease(report of 3 cases)

目的探讨成年人脑卒中后华勒变性的临床及影像学特点。方法回顾性分析3例脑卒中后华勒变性的成年患者的临床及影像学资料,并进行文献复习。结果3例患者均有卒中病史,数月后出现病情复发,查头颅MRI示脑桥内异常信号,且与原发病灶锥体束走形一致,结合患者临床症状,诊断为脑卒中后华勒变性。结论脑卒中后出现华勒变性的患者可以出现临床症候的改变,易误诊为脑梗死,常常预后不佳,临床上应该提高对此病的认识,避免误诊,以改善患者预后,提高生存质量。

Objective To investigate the clinical and imaging features of adult brain stroke with Wallerian degeneration.Methods The clinical and imaging data of 3 adult patients with post-stroke Wallerian degeneration were retrospectively analyzed,and the literature was reviewed.Results All the three patients had a history of stroke,and the disease recurred several months later.Head MRI examination showed abnormal signals in the pontine,which were consistent with the disfigurement of the pyramidal tract of the primary lesion.Combined with the clinical symptoms of the patients,they were diagnosed as post-stroke Wallerian degeneration.Conclusions Patients with Wallerian degeneration after stroke may show changes in clinical symptoms,and are easily misdiagnosed as cerebral infarction,often with poor prognosis.Clinical awareness of this disease should be improved to avoid misdiagnosis,so as to improve the prognosis of patients and improve the quality of life.