重视病理活检,关注自身免疫性肝炎/胰腺炎病理学进展

Value of biopsy in evaluating the pathological progression of autoimmune hepatitis/pancreatitis

肝活检可以直接观察病变的形态学改变,有助于对相关病变进行准确评估,对慢性肝病诊断具有重要价值。自身免疫性肝炎形态复杂,掌握分级分期标准以及重叠综合征判断的同时应关注免疫介导性肝炎和接种新冠疫苗后自身免疫性肝炎形态特征。自身免疫性胰腺炎1型和2型形态明显不同,同时3型自身免疫性胰腺炎需要更多研究。

Liver biopsy is a crucial diagnostic tool for chronic liver diseases,allowing for direct observation of lesion morphology and aiding in precise evaluation.It is especially valuable in cases of autoimmune hepatitis,which exhibits complex morphological characteristics.This includes assessing grading and staging criteria,recognizing overlap syndrome,and considering the morphological features of immune-mediated hepatitis and post-COVID-19 vaccination autoimmune hepatitis.Furthermore,significant morphological differences exist between type 1 and type 2 autoimmune pancreatitis,necessitating further research into type 3 autoimmune pancreatitis.