宫颈癌放疗中患者抑郁情况调查及影响因素分析

Investigation of the depression status of patients with cervical cancer during the radiotherapy and analysis of its influence factors

目的:了解南通地区2个三甲医院就诊的宫颈癌放疗中患者抑郁情况,分析影响因素,精准预防提供指导。方法:选择2019年3月-2023年5月在南通市两所三甲医院实施放疗的1623例宫颈癌患者,于放疗中期采用医院焦虑抑郁量表(HADS)评定患者心理状态予以,获取患者一般资料、诊疗资料、社会支持情况行抑郁的单因素分析,并通过logistic回归筛查出患者抑郁的影响因素。结果:宫颈癌患者放疗中抑郁发生率为29.8%(483/1623);不同学历、家庭月收入、肿瘤分期、治疗方案、毒副反应程度及社会支持情况的患者抑郁发生率存在差异(P<0.05);logistic回归分析显示,患者放疗中发生抑郁的危险因素主要有学历低、家庭月收入低、肿瘤分期晚、同期放化疗、毒副反应程度为中度或重度、社会支持一般或低下。结论:本次调查的宫颈癌患者放疗中发生抑郁发生率较高,学历低、家庭月收入低、肿瘤分期晚、同期放化疗、毒副反应程度为中度或重度、社会支持一般或低下为其危险因素。提示临床为预防患者放疗中出现抑郁情绪,需结合上述因素采取精准的预防干预措施。

Objective:To understand the depression status of patients with cervical cancer during the radiotherapy from two top three hospitals in Nantong,and to analyze the influencing factors of the depression of the patients,in order to provide the guidance for the accurate prevention of the depression of the patients.Methods:A total of 1623 patients with cervical cancer who wanted the radiotherapy from two top three hospitals in Nantong from March 2019 to May2023 were selected in this study.During the mid-term of the radiotherapy of the patients,the hospital anxiety and depression scale(HADS)was applied to assess their depression status.The general information,the diagnostic and treatment data,and the social support of the patient were obtained.Univariate analysis was used to analyze the depression status of the patients,and the influencing factors of the depression of the patients were screened by logistic regression.Results:The incidence of the depression of the patients with cervical cancer during their radiotherapy was 29.8%(483/1623).There was significant difference in the incidence of depression among the patients with different educational levels,among the patients with different monthly family income,among the patients with different tumor staging,among the patients with different treatment plans,among the patients with different degree of toxic side effects,and among the patients with different social support(P<0.05).Logistic regression analysis showed that the risk factors of the depression of the patients during radiotherapy mainly included the low education level,the low monthly family income,the advanced tumor,the concurrent radiotherapy and chemotherapy,the moderate or severe toxicity and the moderate or low social support.Conclusion:This survey shows that the patients with cervical cancer have a higher probability of their depression occurrence during radiotherapy.Th low educational level,the low monthly family income,the advanced tumor,the concurrent radiotherapy and chemotherapy,the moderate or severe toxicity and the moderate and the low social support of the patients are the risk factors of their depression occurrence.Therefore,in order to prevent the depression occurrence of the patients with cervical cancer during radiotherapy,it is necessary to take the accurate preventive intervention measures for the patients based on the above risk factors.