体外受精-胚胎移植治疗后妊娠的重度晚发型卵巢过度刺激综合征患者的护理效果与活产结局的相关性

Correlation between nursing effect and live birth outcome of patients with severe late-onset ovarian hyperstimulation syndrome after in vitro fertilization embryo transfer

目的分析体外受精-胚胎移植治疗后妊娠的重度晚发型卵巢过度刺激综合征患者的护理效果与活产结局的相关性。方法回顾性分析2016年9月-2022年8月期间天津爱维医院收治的90例接受体外受精-胚胎移植治疗后妊娠的重度晚发型卵巢过度刺激综合征患者的病历资料,全部患者均予以相应的护理干预。依据妊娠结局将其分为活产组(n=60)和非活产组(n=30),通过比较两组既往的护理效果,进一步分析不同护理效果与活产结局的相关性。结果两组的平均年龄、不孕年限、不孕症类型、不孕原因、基础FSH、基础LH、基础雌二醇、Gn天数及Gn用量基础资料比较,差异无统计学意义(P>0.05);活产组的既往有IVF失败史的占比(16.67%)明显比非活产组(30.00%)低,P<0.05。两组的体质量指数、腹水、胸水护理结果比较,差异无统计学意义(P>0.05);活产组的SAS、SDS评分均明显低于非活产组,肝功能中度异常比例(6.67%)明显低于非活产组(16.67%),P<0.05。重度晚发型OHSS患者的SAS评分、SDS评分、肝功能中度异常比例与活产结局成反比关系。结论加强重度晚发型OHSS患者的个性化护理干预,帮助患者消除或缓轻负性情绪,积极予以保肝治疗,对提高其活产率有着积极影响。

Objective To analyze the correlation between nursing effect and live birth outcome of patients with severe late-onset ovarian hyperstimulation syndrome after in vitro fertilization embryo transfer treatment.Methods The medical records of 90 patients with severe late-onset ovarian hyperstimulation syndrome who were pregnant after in vitro fertilization embryo transfer from September 2016 to August 2022 were retrospectively analyzed,and all patients were given corresponding nursing intervention.According to the pregnancy outcome,they were divided into live birth group(n=60)and non live birth group(n=30).By comparing the previous nursing effects of the two groups,the correlation between different nursing effects and live birth outcomes was further analyzed.Results There was no significant difference in the average age,infertility years,infertility types,infertility causes,basic FSH,basic LH,basic estradiol,GN days and basic information of GN dosage between the two groups(P>0.05);the proportion of previous IVF failure in the live birth group(16.67%)was significantly lower than that in the non live birth group(30.00%),P<0.05.There was no significant difference in body mass index,ascites and pleural fluid nursing results between the two groups(P>0.05);the SAS and SDS scores of the live birth group were significantly lower than those of the non live birth group,and the proportion of moderate abnormal liver function(6.67%)was significantly lower than that of the non live birth group(16.67%),P<0.05.The SAS score,SDS score and the proportion of moderate abnormal liver function in patients with severe late-onset OHSS were inversely related to the outcome of live birth.Conclusion Strengthening personalized nursing intervention for patients with severe late-onset OHSS,helping patients eliminate or alleviate negative emotions,and actively giving liver protection treatment have a positive impact on improving their live birth rate.