Clinical features and prognostic analysis of transarterial chemoembolization combined with targeted immunotherapy in the treatment of patients with hepatitis B virus-related intermediate- and advanced-stage hepatocellular carcinoma with secondary cholestas

Objective To study the clinical features and prognostic impact of transarterial chemoembolization(TACE),immune checkpoint inhibitors (ICIs),and tyrosine kinase inhibitors (TKIs) combination therapy regimens in the treatment of patients with hepatitis B virus-related intermediate-and advanced-stage hepatocellular carcinoma with secondary cholestasis.