摘要
Excessive accumulation of disulfide molecules,like cystine,can induce disulfide stress and high toxicity in cells,but the reduced form of nicotinamide adenine dinucleotide phosphate can reverse this process and mitigate disulfide stress.
基金
supported by the National Natural Science Foundation of China(No.82272951,82272953)
Beijing Municipal Health Commission(Beijing Demonstration Research Ward BCRW20200303)
Chinese Academy of Medical Sciences(No.2022-I2M-C&T-B-070).
