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SARS-CoV-2 triggers Dickkopf-1(Dkk-1)modulation of T helper cells and lung pathology in mice

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摘要 Severe acute respiratory syndrome coronavirus 2(SARSCov-2)is the etiologic agent of the coronavirus disease 19(COVID-19)pandemic.In viral infections like SARS-CoV-2,a robust anti-viral type 1 immune response,including upregulation of type 1 CD4+T helper cells(Th1),is required for effective viral clearance while minimizing end-organ pathology and collateral tissue damage.
出处 《Genes & Diseases》 SCIE CSCD 2024年第4期9-12,共4页 基因与疾病(英文)
基金 supported by immunophenotyping assessment in a COVID-19 cohort(IMPACC)and has been funded in whole or in part with Federal funds from the National Institute of Allergy and Infectious Diseases,National Institutes of Health,under Contract numbers NO1-Al-25496 and NO1-Al-25482 Nancy Chang,Ph.D.Award for Research Excellence,Baylor College of Medicine.
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