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DLX3(Q178R)mutation delays osteogenic differentiation via H19/miR-29c-3p/KDM5B axis in TDO-iPSCs-derived MSCs

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摘要 Tricho-dento-osseous(TDO)syndrome is a rare autosomal dominant disease resulting from distal-less homeobox 3(DLX3)mutation.1,2 Accumulative bone density in alveolar bone is a clinically favorable phenotype for TDO patients.However,the limited number of bone marrow mesenchymal stem cells(BMSCs)in TDO patients restricts their application.
出处 《Genes & Diseases》 SCIE CSCD 2024年第4期49-52,共4页 基因与疾病(英文)
基金 supported by the National Nature Science Foundation of China(No.81970920,81900983) the Natural Science Foundation of Beijing Municipality,China(No.7232218) the Shanghai Science and Technology Committee Youth Sailing Program(China)(No.19YF1442500).
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