摘要
Tricho-dento-osseous(TDO)syndrome is a rare autosomal dominant disease resulting from distal-less homeobox 3(DLX3)mutation.1,2 Accumulative bone density in alveolar bone is a clinically favorable phenotype for TDO patients.However,the limited number of bone marrow mesenchymal stem cells(BMSCs)in TDO patients restricts their application.
基金
supported by the National Nature Science Foundation of China(No.81970920,81900983)
the Natural Science Foundation of Beijing Municipality,China(No.7232218)
the Shanghai Science and Technology Committee Youth Sailing Program(China)(No.19YF1442500).