摘要
Genome-wide association studies(GWASs)have identified hundreds of loci across the human genome conferring susceptibility to autoimmune diseases(AIDs),some of which are shared between more than two diseases.However,this univariate approach has limitations in detecting complex genotype-phenotype correlations.
基金
financed by Minciencias title proyect"Variantes geneticas y mutaciones genomicas identificadas por secuenciacion de ultima generacion(NGS)en familias colombianas:en busca de marcadores comunes de tautologia autoinmune-No.121577758377"
was partially supported from Universidad del Norte,Barranquilla,Colombia.