吲哚菁绿血管造影技术在评价带蒂皮瓣血流灌注中的研究进展

Research progress of indocyanine green angiography in the evaluation of pedicled flap perfusion

吲哚菁绿(ICG)是一种水溶性生物荧光造影剂,具有红外吸收和发射特性。吲哚菁绿血管造影(ICGA)技术利用这一生物特性,可实现脉管结构及组织血运的可视化以及组织灌注及血流动力学的定量评估,在整形外科及显微外科领域的应用日趋广泛。该综述介绍了ICGA工作原理和方法及其在评估带蒂皮瓣血流灌注方面的研究进展,认为该技术在方法学及结果准确性方面仍具有一定的局限性,临床上对于带蒂皮瓣组织灌注评估时仍需要结合医师临床经验综合评估。

Indocyanine green(ICG)is a water-soluble biological fluorescent contrast agent with infrared absorption and emission characteristics.Indocyanine green angiography(ICGA)takes advantage of this biological property.After ICG is injected into the vascular system,the blood flow dynamic map is captured by high-speed photography or real-time photography,which can realize the visualization of vascular structure and tissue blood supply.Currently,ICGA is the only technique for intraoperative quantitative evaluation of flap blood perfusion,and it is widely used in plastic surgery and microsurgery.According to the relevant literature reports at home and abroad in recent years,this review introduced the working principle and method of ICGA and its research progress in evaluating the blood perfusion of pedicled skin flaps.It is considered that this technique still has some limitations in methodology and accuracy of result,and it is still necessary to combine the clinical experience of doctors in the evaluation of tissue perfusion of pedicled skin flaps.