内科胸腔镜下内脏神经切断术的动物实验

Animal experiment of medical thoracoscopic splanchnotomy

目的通过动物实验初步探索在内科胸腔镜下行内脏神经切断术的可行性。方法对4头实验猪给予静脉麻醉联合肋间神经阻滞麻醉,保留实验动物自主呼吸,应用内科胸腔镜开展内脏神经切断术,记录手术时间、出血量及并发症、技术问题等情况。结果用4头猪开展的内科胸腔镜下内脏神经切断术成功,无术中大出血、脏器损伤及死亡等并发症。结论内科胸腔镜下内脏神经切断术动物试验可行,为内科胸腔镜下内脏神经切断术治疗上腹部癌痛的临床应用提供参考。

Objective To explore the feasibility of medical thoracoscopic splanchnotomy through animal experiments.Methods Four experimental pigs were given intravenous anesthesia combined with intercostal nerve block anesthesia,and preserved the spontaneous breathing state.Splanchnotomy was performed by medical thoracoscope.The operation time,blood loss,complications and technical problems were recorded.Results Medical thoracoscopic splanchnotomy was successfully performed in 4 pigs.There were no complications such as intraoperative hemorrhage,organ injury and death.Conclusion The animal experiment of medical thoracoscopic splanchnotomy is feasible,Which can provide a research basis for the clinical application of medical thoracoscopic splanchnotomy in the treatment of epigastric cancer pain.