针刺治疗神经根型颈椎病机制的研究进展

Research Progress on the Mechanism of Acupuncture Treatment for Cervical Spondylotic Radiculopathy

针刺疗法是治疗神经根型颈椎病的有效方法之一。文章阐述了针刺在改善神经机械压迫、颈部血液循环、炎症因子刺激、氧化应激状态、机体免疫水平方面的作用。重点强调针刺治疗神经根型颈椎病的关键病理环节是增加神经走行空间,改善血管通透性,遏制白介素、TNF-α等始动炎症因子。未来可从炎症介导的JAK1-STAT3、PI3K/Akt/mTOR等分子信号生物通路方向深入研究,以期为今后针刺治疗神经根型颈椎病的靶向机制研究提供参考。

Acupuncture therapy is clearly defined as an effective method for treating cervical spondylotic radiculopathy.This article elaborates on the role of acupuncture in improving neuromechanical compression,cervical blood circulation,inflammatory factor stimulation,oxidative stress state,and decreased immune levels.Emphasis is placed on the key pathological link of acupuncture treatment for CSR,which is to increase the space for neural pathways,improve vascular permeability,and contain interleukin and TNF-αWait for initiating inflammatory factors.In the future,in-depth research can be conducted on the molecular biology of inflammation mediated signaling pathways such as JAK1 STAT3 and PI3K/Akt/mTOR,in order to provide reference for future research on the mechanism of acupuncture treatment of CSR.