摘要
丙烯酰胺作为化妆品风险物质,具有神经毒性和潜在的致癌性,对于儿童的健康和生长发育具有一定危害。目前化妆品中丙烯酰胺的残留研究主要集中于聚丙烯酰胺类原料。本文对29批次市售儿童洗沐产品以及10批次椰油酰胺丙基甜菜碱(CAB)中丙烯酰胺残留进行了分析。结果表明:29批次产品中丙烯酰胺检出率为62%,残留量为0.010~0.151 mg/kg,其中不含聚丙烯酰胺类原料的样品中检出丙烯酰胺的比例为52%,均含有CAB;10批次原料CAB中丙烯酰胺检出率为100%,残留量为0.016~1.082 mg/kg,不同厂家、不同批次差异较大,且丙烯酰胺未作为CAB的风险杂质成分进行控制。丙烯酰胺来源途径较多,本文探索性地提出了化妆品中一种丙烯酰胺来源,并探讨了其产生的原因、安全风险评估以及国内外的监管情况,以期为儿童化妆品的质量控制以及原料监管提供参考。
Acrylamide,a common cosmetic risk substance,has neurological toxicity and potential carcinogenicity,posing risks to children's health and development.At present,research on acrylamide residues in cosmetics mainly focuses on polyacrylamide raw materials.This paper analyzes acrylamide residues in 29 batches of commercially children's wash products and 10 batches of cocamidopropyl betaine(CAB)from different suppliers.The results shows that the detection rate of acrylamide in the 29 batches of products was 62%,with residue levels ranging from 0.010~0.151 mg/kg.In products without polyacrylamide,52%contains acrylamide,all of which include CAB.Besides,the detection rate of acrylamide in 10 batches of CAB raw material is 100%,with residue levels ranging from 0.016~1.082 mg/kg,varying significantly between different batches and manufactures.Acrylamide has not been controlled as a risk impurity component in CAB.Given the multiple sources of acrylamide,this article tentatively proposes an additional source of acrylamide in cosmetics and explores its causes,safety risk assessment,and domestic and foreign regulatory situations,in order to provide references for quality control and raw material supervision in children's cosmetics.
作者
陈岑
姚爽
任江
白利强
CHEN Cen;YAO Shuang;REN Jiang;BAI Li-qiang(Hangzhou DaddyLab Technology Co.,Ltd.)
出处
《中国食品药品监管》
2024年第5期108-113,共6页
China Food & Drug Administration Magazine