血瘀证与IgA肾病的差异性分析

Differential Analysis of Blood Stasis Syndrome and IgA Nephropathy

目的:探讨IgA肾病(IgA nephropathy,IgAN)患者的病理分级、临床指标与血瘀证的相关性。以期完善血瘀型IgAN诊断,为临床治疗有效性提供研究证据。方法:对来源于陕西省中医医院、第一诊断为IgAN的患者进行回顾性调查。共调查40例,采用SPSS 22.0统计软件进行统计,分析血瘀证与病理分级及临床指标的差异性。结果:IgAN血瘀证组病理分级比非血瘀证组高;IgAN血瘀证女性患病概率高于男性;IgAN患者年龄越大患血瘀证的概率更高;IgAN血瘀证患者临床指标相关程度高于非血瘀证患者,具体体现在血瘀证组24 h尿蛋白定量、血肌酐高于非血瘀证组。结论:血瘀证与IgAN病理分级及临床指标呈正相关,血瘀证可作为临床诊断指标之一,为临床治疗有效性提供了研究证据。

Objective:To investigate the correlation between pathological grading,clinical indexes and blood stasis syndrome in patients with IgA nephropathy(IgAN);in order to provide research evidence for the effectiveness of clinical treatment and the improvement of the diagnosis of blood stasis type of IgAN.Methods:A retrospective survey was conducted on patients originating from Shaanxi Provincial Hospital of Traditional Chinese Medicine with the first diagnosis of IgAN.A total of 40 cases were investigated,and SPSS 22.0 statistical software was used to analyze the differences between blood stasis syndrome and pathological grading and clinical indicators.Results:The pathological grading of IgAN group of blood stasis syndrome was higher than that of the non-blood stasis syndrome group;the probability of women with IgAN of blood stasis syndrome was higher than that of men;the older IgAN patients were,the higher the probability of suffering from blood stasis syndrome was;and the degree of relevance of the clinical indexes in patients with IgAN of blood stasis syndrome was higher than that of patients with IgAN of non-blood stasis syndrome,which was reflected in 24-h urinary protein quantity and blood creatinine in the group with blood stasis syndrome were higher than those in the group with non-blood stasis syndrome.Conclusion:Blood stasis syndrome is positively correlated with pathological grading and clinical indexes of IgAN,and blood stasis syndrome can be used as one of the clinical diagnostic indexes,providing research evidence for the effectiveness of clinical treatment.