门冬胰岛素联合地特胰岛素治疗妊娠糖尿病的效果分析

Effect of Insulin Aspartate Combined with Insulin Detemir in the Treatment of Gestational Diabetes Mellitus

目的探讨门冬胰岛素联合地特胰岛素治疗妊娠糖尿病(Gestational Diabetes Mellitus,GDM)的价值。方法回顾性选取寿宁县医院于2021年1月—2023年6月收治的60例GDM患者的临床资料,依照不同治疗方法分为对照组(门冬胰岛素治疗)与观察组(门冬胰岛素联合地特胰岛素治疗),每组30例。比较两组治疗结果。结果治疗前,两组血糖及同型半胱氨酸水平比较,差异无统计学意义(P均>0.05);治疗后,两组血糖及同型半胱氨酸水平均优于治疗前,且观察组优于对照组,差异有统计学意义(P均<0.05);观察组不良妊娠结局总发生率低于对照组,差异有统计学意义(P<0.05)。结论门冬胰岛素与地特胰岛素用于GDM治疗中,可进一步改善血糖指标,能够更好地减少或避免不良妊娠结局发生。

Objective To investigate the value of insulin aspartate combined with insulin detemir in the treatment of gestational diabetes mellitus(GDM).Methods Clinical data of 60 GDM patients admitted to Shouning County Hospi-tal from January 2021 to June 2023 were retrospectively selected,and were divided into control group(insulin aspar-tate treatment)and observation group(insulin aspartate combined with insulin detemir treatment)according to differ-ent treatment methods,with 30 cases in each group.The treatment results of the two groups were compared.Results Before treatment,there was no significant difference in blood glucose and homocysteine levels between the two groups(both P>0.05).After treatment,blood glucose and homocysteine levels in two groups were better than before treatment,and observation group was better than control group,and the differences were statistically significant(both P<0.05).The total incidence of adverse pregnancy outcome in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion The use of insulin aspartate and insulin detemir in the treatment of GDM can further improve blood glucose index,and can better reduce or avoid adverse pregnancy outcomes.