IgG4相关性疾病表现为输尿管肿物1例报告

IgG4-related disease presenting as a ureteral tumor:a case report

IgC4相关性疾病(IgC4-RD)累及输尿管表现为输尿管肿物罕见,本文报道1例女性患者,因体检发现左肾盂输尿管连接处肿物1周就诊。超声及MRI检查示左肾盂输尿管连接处有一长径约3cm的肿物,伴左肾积水,血清IgG4浓度升高。行B超引导下肿物穿刺活检,病理提示淋巴浆细胞浸润,IgG4/IgG>0.5,考虑为IgG4-RD。患者接受糖皮质激素治疗1个月后复查CT见肿物明显缩小,IgG4浓度下降至正常。

IgG4-related disease(IgG4-RD)involving the ureter manifested as a ureteral tumor is rare.This paper reports a case of a female patient who was found with a mass at the left ureteropelvic junction for one week during physical examination.Urinary ultrasound and MRI showed a 3 cm mass at the left ureteropelvic junction with hydronephrosis,and the serum level of IgG4 was elevated.B-ultrasonic guided biopsy of the mass was performed.Histopathological findings showed lymphoplasmic infiltration and the ratio of IgG4/IgG positive cells>0.5.We finally diagnosed IgG4-RD and started using glucocorticoid for her treatment.One month later,CT-scan revealed that the tumor became smaller and the serum IgG4 decreased to the normal range.