绿色合成融入化学实验教学—光催化制备呋喃

Integrating“Green Synthesis”into Chemistry Experiment Teaching-Preparation of Furan by Photocatalytic Reaction

当前医科院校有机化学实验普遍缺乏绿色合成理念的介绍,而且通常需要用到强酸、高温等苛刻反应条件。将绿色合成融入实验教学是一种必然趋势。可见光是一种绿色无污染能源。我们为药学类专业有机化学实验课程设计了一个光催化自由基串联反应的教学实验,以(1-氟乙烯基)苯与2-溴苯乙酮作为原料,在可见光照射下合成呋喃衍生物。本实验具有步骤经济性、条件温和、环境友好等优点,非常适合本科生实验教学和创新型人才的培养。

In view of the lack of green synthesis,and harsh conditions were used,it was an inevitable trend to integrate green synthesis into the experimental teaching.Visible light was an inexhaustible green and sustainable synthesis model.We designed a teaching experiment for experiment course.Using(1-fluorovinyl)benzene and 2-bromoacetophenone,furan derivatives were synthesized under visible light irradiation.This experiment has the advantages of step economy,mild condition,and environmental friendliness,which is suitable for experimental teaching.