漳州市芗城区2012—2023年人间布鲁氏菌病实验室检测结果分析

Analysis of Laboratory Detection Results of Human Brucellosis in Xiangcheng District,Zhangzhou City From 2012 to 2023

目的调查分析漳州市芗城区2012年布鲁氏菌病(以下简称布病)局部暴发的原因、流行特征、连续3年监测点监测结果以及2016—2023年漳州市芗城区出现的布病病例,为预测布病流行趋势、科学预防和控制提供有力依据。方法采用现场流行病学调查、人间布病监测、采样、哨点医院监测及实验室血清学试管凝集试验(serum agglutination test,SAT)对芗城区发生布病及疫情进行调查处置。结果2012—2015年监测点共检测血清标本479份,平均布病抗体阳性率为4.87%,各年度依次为14.43%(14/97)、3.33%(5/150)、1.72%(2/116)、0%(0/116)。哨点医院检测血清标本90份,布病抗体平均阳性率为24.44%,2013年为46.67%(14/30),2014年为16.67%(5/30),2015年为10.00%(3/30)。2016—2023年确诊病例9例。其中2016年2例,2017—2023年各1例。结论2012年漳州市芗城区人间布病疫情的暴发主要与牲畜的屠宰、加工、收购、销售有关。疫情处置后,2013—2023年抗体阳性率逐年走低,所以应继续加强动物间及人间布病跟踪监测,加大宣传教育力度,加强综合防治,严防人间布病的流行。

Objective To investigate and analyze the causes and epidemic characteristics of brucellosis outbreak in Xiangcheng District,Zhangzhou City in 2012,the results of surveillance sites for three consecutive years and brucellosis cases from 2016 to 2023,so as to provide a strong basis for predicting the epidemic trend and scientific prevention and control of brucellosis.Methods Field epidemiological investigation,human brucellosis surveillance,sampling,sentinel hospital surveillance and laboratory serological test tube agglutination(SAT)were used to investigate and treat brucellosis and its epidemic situation in Xiangcheng District.Results A total of 479 serum samples were detected from 2012 to 2015,and the positive rate of bruceopathy antibody was 4.87%,14.43%(14/97),3.33%(5/150),1.72%(2/116),0%(0/116)in each year.90 serum samples were detected in sentinel hospitals,and the positive rate of bruceopathy antibody was 24.44%,46.67%(14/30)in 2013,16.67%(5/30)in 2014 and 10.00%(3/30)in 2015.Between 2016 and 2023,there were 9 confirmed cases.There were 2 cases in 2016 and 1 case each in 2017-2023.Conclusion The outbreak of human brucellosis in the Xiangcheng District,Zhangzhou City in 2012 was mainly related to the slaughter,processing,purchase and sale of livestock.After the treatment of the epidemic,the positive antibody rate continued to decrease year by year.Therefore,it is necessary to continue to strengthen the tracking and monitoring of animal and human brucellosis,strengthen the publicity and education,strengthen the comprehensive prevention and control,and strictly prevent the epidemic of human brucellosis.