住院患者天麻素注射液的不合理用药情况和用药安全性分析

Current situation and safety analysis of irrational use of gastrodin injection in inpatients

目的分析某院天麻素注射液在住院患者中的不合理用药情况和用药安全性。方法从医院信息管理系统中筛选2017年1月至2021年12月使用天麻素注射液的住院患者病例,采集患者基本情况、药品用法用量、用药天数和联合用药等信息,进行统计分析。结果共收集15375例使用天麻素注射液的病例,其中不合理用药占9.53%,不合理用药比例呈逐年下降趋势。最主要的不合理用药类型为用法用量不适宜,占66.95%。药物不良反应发生率为0.33%,患者性别、用药天数和联合用药是发生药物不良反应的影响因素。结论需要重视临床治疗药物监测和药物不良反应的干预,进一步加强天麻素注射液的管理,提高天麻素注射液的规范化使用水平,减少不良反应的发生。

AIM To analyze the clinically irrational use and medication safety of gastrodin injection in inpatients.METHODS Cases of all gastrodin injection inpatients in a hospital from January 2017 to December 2021 were investigated.The basic conditions of the patients,usage and dosage,medication frequency,course of treatment and combined medication were collected.Statistical analysis and special comments were carried out.RESULTS In the investigation of 15375 patients treated with gastrodin injection,the total proportion of irrational drug use was 9.53%,with a gradual declining tendency year by year.The most common type of irrational use was inappropriate dosage and administration,accounting for 66.95%.The incidence of adverse drug reactions was 0.33%.Patient gender and combined drug use were the factors that could affect the occurrence of ADR.CONCLUSION It is necessary to pay attention to clinical medication monitoring and intervention of ADR,further strengthen the management of gastrodin injection,improve the level of standardized use of gastrodin injection,and reduce the occurrence of the ADR.