支气管袖状切除术治疗中心型非小细胞肺癌效果观察

Observation on the Therapeutic Effect of Bronchial Sleeve Resection for Central Non-Small Cell Lung Cancer

目的比较支气管袖状切除术(sleeve lobectomy,SL)与全肺切除术治疗中心型非小细胞肺癌(non-small cell lungcancer,NSCLC)的临床效果,以期为临床合理选择手术方式提供借鉴。方法选择定西市临洮县人民医院2020年6月—2023年6月收治的中心型NSCLC患者60例,依据随机化分组原则分为对照组和观察组各30例。在全身麻醉状态下,对照组接受全肺切除术;观察组接受SL,比较两组患者的手术情况和术后3个月的呼吸功能和生活质量改善情况。结果观察组各手术指标、肺功能指标和世界卫生组织生存质量测量简表各维度评分均优于对照组,差异有统计学意义(P<0.05)。结论相比于传统的全肺切除术,接受SL手术的患者身体损伤较小,住院时间较短;而术后随访显示,接受SL手术的患者肺功能降低程度较低,生活质量较高。

Objective To compare the clinical efficacy of sleeve lobectomy(SL)and total pneumonectomy in the treatment of central non-small cell lung cancer(NSCLC)in order to provide reference for the rational selection of surgical methods in clinical practice.Methods Sixty patients with central NSCLC admitted to Lintao County People's Hospital in Dingxi City from June 2020 to June 2023 were divided into a control group and an observation group according to the principle of randomization,with 30 cases in each group.Under general anesthesia,the control group underwent total pneumonectomy,while the observation group received SL.The surgical outcomes and respiratory function and quality of life improvement at three months after surgery were compared between two groups.Results The observation group had significantly better scores in various surgical indicators,lung function indicators,and scores of the World Health Organization quality of life-bref scale than the control group(P<0.05).Conclusion Compared to traditional pneumonectomy,patients undergoing SL surgery have less physical injury and shorter hospital stay.Postoperative follow-up showed that patients underwent SL surgery had lower levels of pulmonary function decline and higher quality of life.