摘要
目的 采用科学计量学方法可视化分析胆囊癌免疫治疗的整体趋势。方法 通过Web of Science核心数据库(WoSCC)检索与胆囊癌免疫治疗相关的英文文献(论著或综述),发表日期限定为2000年1月1日至2021年12月31日。并以纯文本格式导入VOSviewer 1.6.18.0和CiteSpace 5.1.R8 SE(32-bit)软件。数据使用科学计量学方法进行处理,对作者、国家、机构、高被引文献、共被引、关键词和参考文献进行可视化分析,得出研究热点和趋势。结果 检索获得121篇文献,包括860位作者,306个组织,21个国家/地区和82种期刊。数据显示,美国为胆囊癌免疫治疗领域中发文量最大的国家(40篇),中国(36篇)和日本(14篇)分别位于第二、三。发文量最大的前3名作者分别是Valle JW(5篇)、Javle M(4篇)、Zhu AX(4篇)。中国医学科学院北京协和医学院、克里斯蒂NHS信托基金会、南京医科大学、曼彻斯特大学是发文最多的机构,Cancers是该领域发文最多的期刊。关键词分析显示“immunotherapy”“cholangiocarcinoma”“gallbladder cancer”是高频关键词,目前研究的重点逐渐聚焦于胆囊癌免疫治疗、靶向治疗及相关用药。结论 近21年来胆囊癌免疫治疗领域的发文数量逐渐增加,该领域已成为潜在的热点。美国、中国、日本在这一研究领域占据重要地位。
Objective To visualized analysis the overall trend of immunotherapy for gallbladder cancer by scientometrics.Methods Relevant studies (articles or reviews) related to immunotherapy for gallbladder cancer were searched in the Web of Science Core Collection (WoSCC) database from January 1,2000 to December 31,2021,and input into VOSviewer 1.6.18.0 and CiteSpace 5.1.R8 SE (32-bit) software in plain-text format.All data were processed by using scientometrics.Authors,countries,institutions,highly cited publication,co-citation,keywords and references were subject to visualization analysis,and the research hotspots and trends were obtained.Results 121 studies were retrieved,including 860 authors,306 institutions,21 countries/regions and 82 journals.The data showed that the United States was the country with the largest number of published articles in the field of immunotherapy for gallbladder cancer (n=40),followed by China (n=36) and Japan (n=14).The top three authors with the largest number of published articles were Valle JW (n=5),Javle M (n=4) and Zhu AX (n=4).Chinese Academy of Medical Sciences (Peking Union Medical College),Christie NHS Foundation Trust,Nanjing Medical University and the University of Manchester were the institutions with the largest number of published articles.Cancers was the journal with the largest number of published articles in this field.Keyword analysis indicated that "immunotherapy","cholangiocarcinoma" and "gallbladder cancer" were the high-frequency keywords.Current research hotspots gradually focused on immunotherapy,targeted therapy and drug use for gallbladder cancer.Conclusions In recent 21 years,the number of published articles in the field of immunotherapy for gallbladder cancer has been gradually increased,which has become a potential hotspot.The United States,China and Japan occupy a central position in this field.
作者
张燕
许丁伟
胡满琴
李新成
李翱
黄洁
Zhang Yan;Xu Dingwei;Hu Manqin;Li Xincheng;Li Ao;Huang Jie(Department of Hepatobiliary and Pancreatic Surgery,the Second Affiliated Hospital of Kunming Medical University,Kunming 650101,China)
出处
《中华肝脏外科手术学电子杂志》
CAS
2024年第3期319-327,共9页
Chinese Journal of Hepatic Surgery(Electronic Edition)
基金
云南省科技厅基础研究专项基金资助项目(202101AT070239)。
关键词
胆囊肿瘤
免疫治疗
科学计量学分析
可视化分析
知识图谱
Gallbladder neoplasms
Immunotherapy
Bibliometrics analysis
Visualization analysis
Knowledge map