温胆汤加减治疗失眠的效果分析

Effect of Wendan Decoction in Treating Insomnia

目的:探讨温胆汤加减治疗失眠的临床效果。方法:选取2021年1月—2022年12月中山大学孙逸仙纪念医院收治的失眠患者82例,按照随机数字表法分为两组,各41例。对照组口服艾司唑仑治疗,观察组在对照组基础上加用温胆汤加减治疗,两组持续治疗4周。比较两组患者临床疗效、睡眠质量、睡眠状态、心理状态及不良反应情况。结果:观察组总有效率高于对照组,差异有统计学意义(P=0.043)。治疗后,观察组匹兹堡睡眠质量评定量表评分低于对照组,睡眠潜伏期、觉醒时间短于对照组,睡眠总时间长于对照组,差异有统计学意义(P<0.05)。观察组治疗后焦虑、抑郁评分低于对照组,差异有统计学意义(P<0.05)。两组不良反应比较,差异无统计学意义(P=0.710)。结论:应用温胆汤加减治疗失眠,效果显著,可纠正睡眠状态异常,减轻心理负担,安全可靠。

Objective:To explore the clinical effect of Wendan Decoction on insomnia.Methods:A total of eighty-two insomnia patients admitted to Sun Yat-sen Memorial Hospital of Sun Yat-sen University from January 2021 to December 2022 were selected and divided into two groups according to random number table method,with forty-one patients in each group.The control group was treated with estazolam,and the observation group was treated with Wendan Decoction on the basis of the control group.Both groups were treated for 4 weeks.The clinical efficacy,sleep quality,sleep state,psychological state and adverse reactions were compared between the two groups.Results:The total effective rate of the observation group was higher than that of the control group,the difference was statistically significant(P=0.043);after treatment,the Pittsburgh sleep quality rating scale score of the observation group was lower than that of the control group,the sleep latency and wake time were shorter than that of the control group,and the total sleep time was longer than that of the control group,with statistical significance(P<0.05);the anxiety and depression scores of the observation group were lower than those of the control group after treatment,and the difference was statistically significant(P<0.05);there was no significant difference in adverse reactions between the two groups(P=0.710).Conclusion:Using Wendan Decoction to treat insomnia,the effect is remarkable,can correct abnormal sleep state,reduce psychological burden,safe and reliable.