多层螺旋CT血管造影对急性主动脉综合征的诊断和影像学特征

Analysis on diagnosis and clinical characteristics of MSCTA on acute aortic syndrome

目的:探讨多层螺旋CT血管造影(MSCTA)对急性主动脉综合征(AAS)的诊断及影像学特征。方法:选取2020年6月至2022年7月于阜阳市人民医院诊治的185例疑似AAS患者,在确诊前予以多层螺旋CT(MSCT)平扫、MSCTA检查,以数字血管减影(DSA)诊断结果为“金标准”,采用四格表法计算MSCT平扫,MSCTA的阳性、阴性预测值,采用受试者工作特征(ROC)曲线分析MSCT平扫、MSCTA诊断AAS的ROC曲线下面积(AUC)值、灵敏度及特异度。结果:在185例疑似AAS患者中,以DSA诊断结果为“金标准”确诊82例为急性主动脉综合征;经MSCT平扫检查后,其阳性预测值为68.35%,阴性预测值为73.58%;经MSCTA检测后,阳性预测值为96.30%,阴性预测值为96.15%。MSCTA的诊断确诊率(178/185)高于MSCT平扫(132/185),差异有统计学意义(χ^(2)=42.092,P<0.05)。MSCTA的破口位置(升主动脉、主动脉弓及降主动脉)的检出率高于MSCT平扫,差异有统计学意义(χ^(2)=6.788、4.000、12.974,P<0.05)。ROC曲线分析显示,MSCT平扫、MSCTA诊断AAS的AUC值分别为0.698和0.946。结论:MSCTA诊断AAS具有较高的效能,且AAS多见于主动脉夹层分离和主动脉壁间血肿。

Objective:To explore the diagnosis and clinical characteristics of multi-slice spiral computed tomography angiography(MSCTA)on acute aortic syndrome(AAS).Methods:A total of 185 patients with suspected AAS who were treated in Fuyang People's Hospital from June 2020 to July 2022 were selected,and the diagnostic results of digital vascular subtraction(DSA)were taken as the"gold standard".Before confirmation,MSCT plain scan and MSCTA examination were conducted,and the positively and negatively predictive values of MSCT plain scan and MSCTA were calculated by using four-cell table method.The area under curve(AUC)values,sensitivities and specificities of MSCT plain scan and MSCTA in diagnosing AAS were analyzed by using receiver operating characteristic(ROC)curve model.Results:As the gold standard of DSA diagnostic results,82 cases of 185 patients with suspected AAS were confirmed as AAS.The positively and negatively predictive values of MSCT plain scan were 68.35%and 73.58%,respectively.The positively and negatively predictive value of MSCTA examination were 96.30%and 96.15%,respectively.The diagnostic accuracy of MSCTA was significantly higher than that of MSCT plain scan(χ^(2)=42.092,P<0.05).The detection rates of laceration locations(ascending aorta,aortic arch and descending aorta)in MSCTA were significantly higher than that in MSCT plain scan(χ^(2)=6.788,4.000,12.974,P<0.05),respectively.ROC curve analysis showed that the AUC values of MSCT plain scan and MSCTA were respectively 0.698 and 0.946 in diagnosing AAS.Conclusion:MSCTA has a higher efficiency in diagnosing AAS,and AAS mostly includes the aortic dissection separation and aortic intramural hematoma.