肌骨超声特征评分与类风湿关节炎患者病情严重程度的相关性

Correlation between musculoskeletal ultrasound feature score and severity of rheumatoid arthritis

目的:探讨肌骨超声特征评分与类风湿关节炎患者病情严重程度的相关性。方法:回顾性分析2021年1月至2022年12月该院收治的70例类风湿关节炎患者的临床资料,根据类风湿关节炎疾病活动度评价表(DAS28)评分将其分为缓解期组(n=12,DAS28评分≤2.6分)、低活动期组(n=18,2.6分5.1分),比较四组肌骨超声特征评分,并采用Pearson相关性分析其与类风湿关节炎患者病情严重程度的相关性。结果:四组关节积液、滑膜增生、关节骨侵蚀及滑膜内血流信号等肌骨超声特征评分为高活动期组>中活动期组>低活动期组>缓解期组,差异均有统计学意义(P<0.05);Pearson相关性分析结果显示,关节积液、滑膜增生、关节骨侵蚀及滑膜内血流信号等肌骨超声特征评分均与类风湿关节炎患者病情严重程度呈正相关(r>0,P<0.05)。结论:关节积液、滑膜增生、关节骨侵蚀及滑膜内血流信号等肌骨超声特征评分均与类风湿关节炎患者病情严重程度呈正相关。

Objective:To investigate correlations between musculoskeletal ultrasound feature score and severity of rheumatoid arthritis.Methods:The clinical data of 70 patients with rheumatoid arthritis admitted to this hospital from January 2021 to December 2022 were retrospectively analyzed.They were divided into remission group(n=12,DAS28 score≤2.6),low activity group(n=18,2.6<DAS28 score≤3.2),middle activity group(n=22,3.2<DAS28 score≤5.1),and high activity group(n=18,DAS28 score>5.1)according to the rheumatoid arthritis disease activity evaluation table(DAS28)score.The musculoskeletal ultrasound feature scores of the four groups were compared.Pearson correlation analysis was used to analyze its correlation with the severity of rheumatoid arthritis.Results:The scores of musculoskeletal ultrasound features such as joint effusion,synovial hyperplasia,joint bone erosion and synovial bloodflow signals in the four groups were:high activity group>middle activity group>low activity group>remission group,and the differences were statistically significant(P<0.05).The Pearson correlation analysis showed that the musculoskeletal ultrasound feature scores of joint effusion,synovial hyperplasia,joint bone erosion,and synovial bloodflow signals were positively correlated with the severity of rheumatoid arthritis(r>0,P<0.05).Conclusions:The scores of musculoskeletal ultrasound features such as joint effusion,synovial hyperplasia,joint bone erosion and synovial bloodflow signals are positively correlated with the severity of rheumatoid arthritis.