有氧联合抗阻运动对血液透析患者干预效果的meta分析

Meta analysis of interventional effect of aerobic combined resistance exercise on hemodialysis patients

目的系统评价有氧联合抗阻运动对血液透析(HD)患者步行能力、心肺耐力、透析充分性和生活质量的干预效果。方法检索PubMed、Cochrane Library、Embase、Ovid、Web of Science、中国知网、维普、万方与中国生物医学文献服务系统(SinoMed)数据库公开发表的关于有氧联合抗阻运动对HD患者干预效果的随机对照试验;检索时间为建库起至2021年5月28日;纳入的文献采用RevMan5.4软件进行分析。结果共纳入24项研究,1086例研究对象;结果显示,与对照组(采用常规护理或进行无阻力肢体活动)比较,干预组(有氧联合抗阻运动)HD患者步行能力、心肺耐力和部分生活质量维度明显改善;HD过程中干预组患者透析充分性较对照组明显改善。结论有氧联合抗阻运动能够提升HD患者身体功能、生活质量和透析充分性,建议结合具体情况,鼓励患者进行有氧联合抗阻运动。

Objective To systematically assess the interventional effects of aerobic combined resistance exercise on walking ability,cardiorespiratory endurance,dialysis adequacy and quality of life in the patients with hemodialysis(HD).Methods The published randomized controlled trials on the interventional effects of aerobic combined resistance exercise in HD patients were retrieved from the databases of PubMed,Cochrane Library,Embase,Ovid,Web of Science,CNKI,VIP,Wanfang and China Biomedical Literature Service System(SinoMed).The retrieval time was from the database establishment to May 28,2021;the included literatures were analyzed by using RevMan 5.4 software.Results A total of 24 studies with 1086 research subjects were included.The results showed that compared with the control group(adopting the usual care or conducting no-resistance limb movement),the walking ability,cardiopulmonary endurance and the dimensions of partial quality of life in the HD patients of the intervention group(aerobic combined resistance exercise)were significantly improved.The dialysis adequacy during dialysis in the intervention group was significantly improved compared with that in the control group.Conclusion Aerobic combined resistance exercise could improve the physical function,quality of life and dialysis adequacy in HD patients,and it is recommended that the patients are encouraged to conduct the aerobic combined resistance exercise by combining with the specific situation.