苗药治疗糖脂代谢性疾病的研究进展

Research Progress of Miao Medicine in the Treatment of Glucolipid Metabolic Disease

糖脂代谢性疾病(Glucolipid metabolic disease,GLMD)是一类与糖、脂代谢紊乱密切相关的疾病,主要包括高脂血症、糖尿病、非酒精性脂肪性肝病、动脉粥样硬化等,发病率逐年上升,严重威胁着国民健康。苗医药是我国传统医药的重要组成部分,资源丰富且极具特色,在治疗糖脂代谢病上具有优势,但目前尚未见有关苗药治疗该类疾病的系统文献梳理。本文以《中华本草·苗药卷》中记载的常用苗药为主,通过检索近年来苗药治疗糖脂代谢病的相关文献,对其药理作用、作用机制、临床应用的研究进展进行归纳总结,以期为苗药的深入研究开发与利用提供参考依据和研究思路。

Glucolipid Metabolic Disease(GLMD)is a group of diseases closely related to disorders of glucose and lipid metabolism,mainly including hyperlipidemia,non-alcoholic fatty liver,diabetes,atherosclerosis,etc.The incidence is increasing year by year and poses a serious threat to national health.Miao medicine is an important part of traditional medicine in China,with rich resources and great characteristics,and has advantages in the treatment of glucolipid metabolic disease,but there is no systematic literature combing about Miao medicine for this kind of disease.In this paper,we reviewed the literature related to the treatment of glucolipid metabolic diseases by Miao medicine in recent years through data search,based on the commonly used Miao medicines recorded in the Chinese Materia Medica,and summarized the research progress of its pharmacological effects,mechanism of action,and clinical application,in order to provide reference basis and research ideas for the in-depth research development and utilization of Miao medicine.