急性ST段抬高心肌梗死不同治疗方式的临床疗效观察

The clinical efficacy of different treatment methods for acute ST-segment elevation myocardial infarction

目的:探讨STEMI不同治疗方式的临床疗效观察。方法:选取我院2018年5月至2020年6月的106例STEMI患者的临床资料,按照治疗方法分为急诊PCI组、溶栓后早期PCI组、溶栓后择期PCI组,比较三组患者临床疗效。结果:三组LVDd、LVEF、NGF、cMyBP-C比较,差异有统计学意义(P<0.05);治疗后7d、6个月,LVDd急诊PCI组低于其余两组,而LVEF急诊PCI组高于其余两组(P<0.05);PCI术后急诊PCI组的NGF、cMyBP-C低于其余两组(P<0.05);TIMI血流分级三组比较差异无统计学意义(P>0.05)。急诊PCI组的不良事件总发生率低于其余两组(P<0.05)。结论:不同PCI时机对急性ST段抬高型心肌梗死患者的心功能均有不同程度的改善,但急诊PCI对患者的NGF、cMyBP-C有较大的改善作用,且不良反应较少,对于有指征的患者应在临床上对患者尽早行PCI术。

Objective:To explore the clinical efficacy of different treatment methods for STEMI.Method:Clinical data of 106 STEMI patients in our hospital from May 2018 to June 2020 were selected and divided into emergency PCI group,early PCI group after thrombolysis,and selective PCI group after thrombolysis according to treatment methods.The clinical efficacy of the three groups of patients was compared.Results:there was a statistically significant difference in LVDd,LVEF,NGF,and cMyBP-C among the three groups(P<0.05);At 7 days and 6 months after treatment,the LVDd emergency PCI group was lower than the other two groups,while the LVEF emergency PCI group was higher than the other two groups(P<0.05);The NGF and cMyBP-C levels in the emergency PCI group after PCI were lower than those in the other two groups(P<0.05);There was no statistically significant difference in TIMI blood flow classification among the three groups(P>0.05).The overall incidence of adverse events in the emergency PCI group was lower than the other two groups(P<0.05).Conclusion:Different timing of PCI has varying degrees of improvement in cardiac function in patients with acute ST segment elevation myocardial infarction.However,emergency PCI has a significant improvement effect on NGF and cMyBP-C in patients,and there are fewer adverse reactions.For patients with indications,PCI should be performed as early as possible in clinical practice..