聚酰胺/银纺丝SERS基底的制备与应用研究

Synthesis and application of polyamide/silver composite for SERS

表面增强拉曼散射(SERS)是通过吸附在粗糙金属表面或金属纳米结构上的分子与金属表面发生的等离子共振相互作用而引起的拉曼散射增强。为提高基底的比表面积,选择具有良好化学稳定性的聚酰胺(PA),将其通过静电纺丝的方式制备出纳米纤维膜。该试验采用静电纺丝方式制备了PA纳米纤维膜,探究13%~20%之间4种不同浓度的PA溶液的纺丝效果,获得稳定性较好且纤维直径约为100 nm的PA纺丝膜。再利用化学结合的方法,在PA纤维上负载不同粒径的银纳米粒子(Ag NPs),进而得到PA/Ag纺丝膜。将30 nm和58 nm的PA/Ag纺丝膜分别用于拉曼分析,以罗丹明6G(R6G)为探针分子衡量PA/Ag纺丝膜材料的SERS性能,检测限约为10-10 M。58 nm PA/Ag纺丝膜基底拥有更出色的重现性,进一步将其用于叶酸的拉曼检测,基底能够检测到低浓度10-8 M的叶酸,具有良好的SERS效果。

Surface enhancement of Raman scattering(SERS)is an enhancement of Raman scattering caused by surface plasmon resonance interactions between molecules adsorbed on rough metal surfaces or metal nanostructures and metal surfaces.To increase the surface area of the substrate,polyamide(PA)with excellent chemical stability was used to fabricate nanofiber membranes by electrospinning.In order to investigate the effects on the structure and morphology of fiber membranes,this experiment explored the spinning effects of four different mass fraction of PA solution from 13%to 20%to obtain a PA spinning membrane with good stability and a fiber diameter of approximately 100 mm.After that,then the PA/Ag Spinning membrane was obtained by loading silver nanoparticles(Ag NPs)with different particle sizes on the PA fiber by chemical combination method.PA/Ag spinning membranes of 30 nm and 58 nm were used for Raman analysis,respectively,and rhodamine 6G(R6G)probe molecule was used to measure the SERS performance of PA/Ag fiber membrane materials,the detection limit was approximately 10-10 M.The 58 nm PA/Ag spinning membrane has better reproducibility and can be further used for the Raman detection of folic acid.It was found that 10-8 M folic acid can be detected by the constructed PA/Ag composite substrate,demonstrating the good SERS performance of this substrate.