苯磺酸瑞马唑仑麻醉对老年无痛胃肠镜检查患者血流动力学的影响

Effect of remazolam benzenesulfonate anesthesia on hemodynamics in elderly patients undergoing painless gastrointestinal microscopy

目的探讨苯磺酸瑞马唑仑麻醉对老年无痛胃肠镜检查患者血流动力学的影响。方法选取2021年1月—2023年本院6月收治的100例无痛胃肠镜检查者为研究对象,采取随机数字表法分为对照组与研究组(各50例)。对照组实施丙泊酚+阿芬太尼麻醉,研究组实施苯磺酸瑞马唑仑+阿芬太尼麻醉。对比两组不同时间点[麻醉诱导前(T0)、麻醉诱导3 min(T1)、麻醉诱导10 min(T2)及苏醒时(T3)]血流动力学指标及麻醉质量。结果与T0时间点相比,T1~T3时间点患者的心率、血氧饱和度及平均动脉压指标均降低,但研究组患者心率、血氧饱和度及平均动脉压指标降低幅度均小于同期对照组,并且在T3时间点,两组患者心率、血氧饱和度及平均动脉压指标有所回升(P<0.05)。研究组诱导起效时间长于对照组,苏醒时间、离室时间短于对照组(P<0.05)。结论在老年患者行无痛胃肠镜检查过程中积极实施苯磺酸瑞马唑仑+阿芬太尼药物麻醉,可取得更为理想的麻醉效果,并且对于血流动力学影响较小。

Objective To investigate the effect of remazolam benzenesulfonate anesthesia on hemodynamics in elderly patients undergoing painless gastroenteroscopy.Methods A total of 100 patients with painless gastroenteroscopy in Jin'an Distric Hospital of Fuzhou City from January 2021 to June 2023 were selected and divided into a control group and a study group with 50 cases in each group by random number table method.The control group was anesthetised with propofol+afentanil,and the study group was anesthetised with remazolam benzenesulfonate+afentanil.The hemodynamics and anesthesia quality of the two groups were compared at different time points[before anesthesia induction(T0),3 min of anesthesia induction(T1),10 min of anesthesia induction(T2),and recovery(T3)].Results Compared with T0,the heart rate,blood oxygen saturation,and mean arterial pressure of patients at T1-T3 decreased,but the three indicators of patients in the study group decreased less than those of the control group,and at T3,the three indicators of patients in the two groups rebounded(P<0.05).The onset time of induction in the study group was longer than that in the control group,and the time of awakening and leaving the surgery room was shorter than that in the control group(P<0.05).Conclusion Actively implementing remazolam benzenesulfonate+alfentanil anesthesia during painless gastroenteroscopy in elderly patients can achieve ideal anesthesia effects and have less impacts on hemodynamics.