Marshall静脉无水乙醇消融治疗持续性房颤的临床疗效分析

Analysis of Clinical Effect of Marshall Vein Anhydrous Ethanol Ablation in the Treatment of Persistent Atrial Fibrillation

目的:探索Marshall静脉无水乙醇消融联合导管射频消融术治疗持续性房颤的有效性和安全性。方法:选取2021年8月—2022年6月就诊于荆州市中心医院的120例持续性房颤患者,按照是否行Marshall静脉无水乙醇消融术分为两组,对照组行导管射频消融术(n=60),试验组行Marshall静脉无水乙醇消融联合导管射频消融术(n=60)。比较两组患者二尖瓣峡部阻滞成功率、术后房颤复发情况及手术并发症。结果:试验组患者二尖瓣峡部阻滞成功率显著高于对照组(98.33%vs 68.33%,P<0.001),术后12个月时,试验组的房颤复发率显著低于对照组(15.00%vs 36.67%,P<0.05)。两组患者术后均未出现严重并发症。结论:相较于单纯导管射频消融术,Marshall静脉无水乙醇消融联合导管射频消融治疗持续性房颤疗效更优且远期复发率更低,值得临床推广应用。

Objective:To explore the effectiveness and safety of Marshall vein anhydrous ethanol ablation combined with catheter radiofrequency ablation in the treatment of persistent atrial fibrillation.Methods:A total of 120 patients with persistent atrial fibrillation who were admitted to Jingzhou Central Hospital from August 2021 to June 2022 were selected and divided into two groups according to whether they underwent Marshall vein anhydrous ethanol ablation.The control group underwent catheter radiofrequency ablation(n=60),while the experimental group underwent Marshall vein anhydrous ethanol ablation combined with catheter radiofrequency ablation(n=60).The success rate of mitral isthmus block,postoperative atrial fibrillation recurrence,and surgical complications were compared between the two groups.Results:The success rate of mitral isthmus block in the experimental group was significantly higher than that in the control group(98.33%vs 68.33%,P<0.001).At 12 months postoperatively,the recurrence rate of atrial fibrillation in the experimental group was significantly lower than that in the control group(15.00%vs 36.67%,P<0.05).No severe complications occurred in both groups after surgery.Conclusion:Compared with catheter radiofrequency ablation alone,the Marshall vein anhydrous ethanol ablation combined with catheter radiofrequency ablation for the treatment of persistent atrial fibrillation has better efficacy and lower long-term recurrence rate,which is worthy of clinical promotion and application.