奶牛卵泡颗粒细胞在卵泡发育中的作用机制

The Mechanism of Follicular Granulosa Cells in Follicular Development in Dairy Cows

随着奶牛产奶量的提高,我国奶业产业链也在不断优化和升级,朝着现代化、规范化和国际化的方向迈进。然而,高产奶牛的繁殖性能却在逐渐降低,目前,这已成为奶牛相关研究工作者面临的共同问题。卵泡发育与繁殖效率关系密切,卵泡正常发育是奶牛发情、排卵等繁殖活动的先决条件。其中,卵泡颗粒细胞能够与卵母细胞和卵泡膜细胞相互作用分泌多种激素和因子,同时,作为多种激素和细胞因子的受体影响卵泡发育。因此,本文总结了关于卵泡颗粒细胞功能与卵泡发育的相关研究,并以卵泡颗粒细胞在卵泡发育过程中的作用和颗粒细胞对卵母细胞的影响为重点进行综述,以期为今后相关研究提供理论参考。

With the improvement of milk production of dairy cows,China′s dairy industry chain is also continuously optimized and upgraded,making progress towards modernization,standardization and internationalization.However,the reproductive performance of high producing dairy cows is gradually decreasing,which has become a common problem faced by dairy cows related researchers.Follicle development is closely related to reproductive efficiency,and normal follicle development is a prerequisite for reproductive activities such as estrus and ovulation.During follicle development,follicular granulosa cells can interact with oocytes and theca cells to produce a variety of hormones and factors,and act as receptors for a variety of hormones and factors to affect follicular development.Therefore,this paper summarized the research on the function of follicular granulosa cells and follicular development,and focused on the role of follicular granulosa cells in follicular development and the influence of granulosa cells on oocytes,in order to provide theoretical reference for future related studies.