中成药联合西医基础治疗老年慢性支气管炎疗效Meta分析

Meta-analysis of the Efficacy of Chinese Patent Medicine Combined with Western Medicine for the Treatment of Senile Chronic Bronchitis

系统评估中成药联合西医基础治疗老年慢性支气管炎的临床效果,为有效控制和缓解老年慢性支气管炎临床症状的深度研究提供依据。应用计算机在中国知网(CNKI)、中文科技期刊数据库(维普网)、中国学术期刊数据库(万方数据)等数据库中检索和筛选相关文献,采用Cochrane系统提供的ROB 2.0评估软件进行文献偏倚风险评估、协作网提供的Revman 5.4.1软件进行统计分析。对11篇文献的Meta分析结果显示,与对照组相比,治疗组能显著提高老年慢性支气管炎的临床效果(RR=1.22,95%CI[1.25,1.29])、缩短咳嗽消失时间(MD=-2.96,95%CI[-4.09,-1.84])、啰音消失时间(MD=-2.97,95%CI[-4.19,-1.74])、喘息消失时间(MD=-2.13,95%CI[-2.71,-1.54])并改善其用力肺活量(FVC)(MD=0.59,95%CI[0.46,0.71])、呼气峰值流速(PEF)(MD=1.06,95%CI[0.79,1.33])、FEV1%占预计值百分比(FEV1%)(MD=8.69,95%CI[6.52,10.89]),表明中成药联合西医基础治疗可以提高老年慢性支气管炎患者的临床效果,缩短症状控制时间并改善患者的肺功能。

To access the efficacy of Chinese patent medicine combined with western medicine in the treatment of senile chronic bronchitis,and provide reference for the deep research of effective control and relief of senile chronic bronchitis,the study searches and screens related papers in CNKI,VIP and WanFang Data,etc.ROB 2.0 evaluation software provided by the Cochrane system is used for literature bias risk assessment,and the Revman 5.4.1 software provided by the collaborative network is used for statistical analysis.Results of Meta-analysis of 11 papers show that compared with the control group,Chinese medicine improved clinical efficiency(RR=1.22,95%CI[1.25,1.29]),and shortened time to disappearance of cough(MD=-2.96,95%CI[-4.09,-1.84]),time to disappearance of rales(MD=-2.97,95%CI[-4.19,-1.74]),time to disappearance of wheeze(MD=-2.13,95%CI[-2.71,-1.54]),and improvement in FVC(MD=0.59,95%CI[0.46,0.71]),PEF(MD=1.06,95%CI[0.79,1.33])and FEV1%(MD=8.69,95%CI[6.52,10.89]).Chinese patent medicine combined with western medicine can improve the clinical efficacy of senile chronic bronchitis,shorten the time to symptom control,and improve lung function.