磁共振弥散张量成像在膝关节软骨损伤分级诊断中的临床价值探究

The clinical value of magnetic resonance diffusion tensor imaging in the classification diagnosis of knee cartilage injury

目的:分析磁共振弥散张量成像(DTI)在膝关节软骨损伤分级诊断中的临床价值。方法:选取常熟市第一人民医院2022年2月—2024年2月收治的80例膝关节软骨损伤患者为损伤组,以同期就诊的80例伴有膝关节不适无关节软骨损伤的健康成年人为未损伤组,均进行DTI检查,比较两组各向异性分数(FA)值、表观弥散系数(ADC)值,统计膝关节软骨Recht-MRI分级结果,比较不同Recht-MRI分级组FA值、ADC值,采用Spearman分析FA值、ADC值与Recht-MRI分级的相关性。结果:损伤组FA值低于未损伤组,ADC值高于未损伤组(P<0.001)。80例患者中,膝关节软骨Recht-MRI分级以Ⅱ级占比率最高。Ⅳ级患者FA值低于Ⅲ级、Ⅱ级、Ⅰ级患者,Ⅲ级患者FA值低于Ⅱ级、Ⅰ级低,Ⅱ级患者FA值低于Ⅰ级;Ⅳ级患者ADC值高于Ⅲ级、Ⅱ级、Ⅰ级患者,Ⅲ级患者ADC值高于Ⅱ级、Ⅰ级,Ⅱ级患者ADC值高于Ⅰ级,差异均有统计学意义(P<0.05)。FA值与Recht-MRI分级呈负相关,ADC值与Recht-MRI分级呈正相关。结论:DTI通过定量检测FA值、ADC值,可对膝关节软骨损伤程度作出准确评价,指导临床及早给予针对性治疗。

Objective To analyze the clinical value of magnetic resonance image diffusion tensor imaging(DTI)in the classification of knee cartilage injury.Methods Eighty patients with knee joint cartilage injury admitted in the Changshu No.1 People's Hospital from February 2022 to February 2024 were selected as the injury group,and 80 healthy adults with knee joint discomfort and no articular cartilage injury treated during the same period were selected as the uninjured group.DTI examination was performed on all patients.The anisotropy fraction(FA)and apparent diffusion coefficient(ADC)values of the two groups were compared,and the results of knee cartilage Recht-MRI grading were statistically analyzed.The FA values and ADC values of different Recht-MRI grading groups were compared,and the correlation between FA values and ADC values and Recht-MRI grading was analyzed by Spearman.Results The FA value of the injured group was significantly lower than that of the uninjured group,and the ADC value of the was significantly higher than that of the uninjured group(P<0.001).The Recht-MRI grade of knee cartilage in 80 patients was the highest in gradeⅡ.The FA value of gradeⅣpatients was lower than that of gradeⅢ,Ⅱ,andⅠpatients.The FA value of gradeⅢpatients was lower than that of gradeⅡandⅠpatients,and the FA value of gradeⅡpatients was lower than that of gradeⅠpatients.The ADC value of GradeⅣpatients was higher than that of GradeⅢ,Ⅱ,andⅠpatients,and the ADC value of GradeⅢpatients was higher than that of GradeⅡandⅠpatients,the ADC value of GradeⅡpatients was higher than that of GradeⅠpatients,and the differences were statistically significant(P<0.05).FA value was negatively correlated with Recht-MRI grading,ADC value was positively correlated with Recht-MRI grading.Conclusion DTI can accurately evaluate the degree of knee cartilage injury through quantitative detection of FA value and ADC value,and guide clinical early targeted treatment.