CT灌注成像检查应用于宫颈癌分期及淋巴结转移的诊断价值分析

The diagnostic value analysis of CT perfusion imaging in cervical cancer staging and lymph node metastasis

目的:探究CT灌注成像检查在宫颈癌分期、淋巴结转移诊断中的价值。方法:选择2021年7月—2023年8月临沂市中心医院收治的宫颈癌患者80例,所有患者均行CT灌注成像检查。以病理学检查结果为“金标准”,分析CT灌注成像的检查结果,对比不同宫颈癌分期患者CT灌注参数水平,对比淋巴结转移及未转移患者CT灌注参数,分析CT灌注参数在诊断宫颈癌淋巴结转移中的应用价值。结果:经CT灌注成像检查在宫颈癌分期中诊断准确率为92.50%(74/80)。Ⅲ期宫颈癌患者BF水平低于Ⅱ期及Ⅰ期,PS水平高于Ⅱ期及Ⅰ期,差异有统计学意义(P<0.001)。无淋巴结转移的宫颈癌患者BF水平高于发生淋巴结转移患者,PS水平低于发生淋巴结转移患者,差异有统计学意义(P<0.001)。CT灌注参数中BF诊断价值较高,灵敏度为0.862,特异度为0.682,AUC为0.843;PS诊断价值略低,灵敏度为0.672,特异度为0.818,AUC为0.817。结论:CT灌注成像检查在明确宫颈癌分期及淋巴结转移中具有较高的临床应用价值,通过分析各指标水平变化以判断患者分期状况及淋巴转移情况,可为临床诊疗提供有效参考,具有较高的临床推广应用价值。

Objective To explore the value of CT perfusion imaging in the staging and lymph node metastasis diagnosis of cervical cancer.Methods A total of 80 patients with cervical cancer admitted to Linyi Central Hospital from July 2021 to August 2023 were selected.All patients underwent CT perfusion imaging,using pathological examination results as the"gold standard".The results of CT perfusion imaging were analyzed to compare the level of CT perfusion parameters in patients with different stages of cervical cancer,compare the CT perfusion parameters in patients with and without lymph node metastasis,and analyze the application value of CT perfusion parameters in the diagnosis of cervical cancer lymph node metastasis.Results The diagnostic accuracy of CT perfusion imaging in cervical cancer staging was 92.50%(74/80).The blood flow(BF)level of stageⅢcervical cancer patients was lower than that of stageⅡand stageⅠ,and the permeability surface(PS)level was higher than that of stageⅡand stageⅠ,the difference was statistically significant(P<0.001).The BF level in cervical cancer patients without lymph node metastasis was higher than that in patients with lymph node metastasis,the PS level was lower than that of patients with lymph node metastasis,with significant differences(P<0.001).The diagnostic value of BF in CT perfusion parameters was higher,the sensitivity was 0.862,the specificity was 0.682 and the area under the curve(AUC)was 0.843.The diagnostic value of PS was slightly lower,the sensitivity was 0.672,the specificity was 0.818,and the AUC was 0.817.Conclusion CT perfusion imaging has high clinical application value in clarifying the staging and lymph node metastasis of cervical cancer.By analyzing the changes in various indicators to determine the patient's staging status and lymph node metastasis,it can provide effective reference for clinical diagnosis and treatment,and has high clinical promotion and application value.