红细胞分布宽度与维持性血液透析患者心胸比率的相关性研究

Study on the Correlation Between Red Blood Cell Distribution Width and Cardiothoracic Ratio in Maintenance Hemodialysis Patients

目的探讨红细胞分布宽度(RDW)与维持性血液透析(MHD)患者心胸比率(CTR)的相关性。方法选取2022年6月-2023年6月玉林市第一人民医院收治的106例MHD患者为研究对象,根据心胸比率(CTR)结果分为心胸比率增大组76例(CTR≥0.5)与对照组30例(CTR<0.5)。比较两组患者的一般资料与实验室检查结果,采用单因素与多因素Logistic回归模型分析CTR增大的相关因素,分析RDW对MHD患者CTR增大的预测价值。结果心胸比率增大组RDW高于对照组,转铁蛋白饱和度低于对照组,差异有统计学意义(P<0.05);单因素分析显示,年龄、RDW、红细胞压积、血清白蛋白与CTR增大相关(P<0.05);多因素Logistic回归模型分析显示,年龄(OR=1.038,95%CI:1.001~1.076,P=0.046)、RDW(OR=1.457,95%CI:1.081~1.964,P=0.013)是CTR增大的独立危险因素。结论RDW是MHD患者CTR增大的独立危险因素,或可作为预测MHD患者CTR增大的可重复性和易于评估的指标。

Objective To investigate the correlation between red blood cell distribution width(RDW)and cardiothoracic ratio(CTR)in maintenance hemodialysis(MHD)patients.Methods A total of 106 MHD patients admitted to the First People's Hospital of Yulin City from June 2022 to June 2023 were selected as the research objects.According to the results of cardiothoracic ratio(CTR),they were divided into cardiothoracic ratio increase group(76 patients,CTR≥0.5)and control group(30 patients,CTR<0.5).The general data and laboratory examination results of the two groups were compared.Univariate and multivariate Logistic regression models were used to analyze the related factors of increased CTR,and the predictive value of RDW for increased CTR in MHD patients was analyzed.Results The RDW of the cardiothoracic ratio increased group was higher than that of the control group,and the transferrin saturation was lower than that of the control group,the difference was statistically significant(P<0.05);univariate analysis showed that age,RDW,hematocrit,and serum albumin were associated with increased CTR(P<0.05).Multivariate Logistic regression analysis showed that age(OR=1.038,95%CI:1.001-1.076,P=0.046)and RDW(OR=1.457,95%CI:1.081-1.964,P=0.013)were independent risk factors for increased CTR.Conclusion RDW is an independent risk factor for increased CTR in MHD patients,and may be used as a repeatable and easy-to-assess indicator for predicting increased CTR in MHD patients.