摘要
心脑血管疾病是全球死亡率较高的疾病之一,严重影响人类健康。临床上常通过检测心肌损伤标志物的异常数值反映心肌损伤的严重程度,并作为心肌损伤(异常)的筛查、诊断以及预后的参考指标。介绍了金属有机骨架(MOFs)材料及其复合材料的分类,并综述了基于MOFs复合材料的电化学蛋白质传感器、电化学免疫传感器和电化学适配体传感器在检测心肌损伤标志物方面的研究进展。
Cardiovascular and cerebrovascular diseases are one of the diseases with the highest mortality rate in the world,seriously affecting human health.Clinically,the abnormal values of myocardial injury markers are often detected to reflect the severity of myocardial injury and used as a reference index for screening,diagnosis,and prognosis of myocardial injury(abnormality).In this paper,the classification of metal-organic frameworks(MOFs)and their composites were introduced,and the research progress of electrochemical protein sensors,electrochemical immunosensors,and electrochemical aptamer sensors based on MOF composites for the detection of markers of myocardial injury was reviewed.
作者
吴春艳
穆文迪
潘洪志
Wu Chunyan;Mu Wendi;Pan Hongzhi(School of Health Science and Engineering,University of Shanghai for Science and Technology,Shanghai 200093,China;Collaborative Research Center,Shanghai University of Medicine and Health Sciences,Shanghai 201318,China)
出处
《国际生物医学工程杂志》
CAS
2024年第2期180-187,共8页
International Journal of Biomedical Engineering
基金
国家自然科学基金(82273687、81973097)。
